FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014658918> ?p ?o ?g. }

• W2014658918 endingPage "773.e1" @default.
• W2014658918 startingPage "768" @default.
• W2014658918 abstract "ObjectiveTo define subgroups at high risk of local recurrence (LR) after surgery for non–small cell lung cancer using a recursive partitioning analysis (RPA).MethodsThis Institutional Review Board–approved study included patients who underwent upfront surgery for I-IIIA non–small cell lung cancer at Duke Cancer Institute (primary set) or at other participating institutions (validation set). The 2 data sets were analyzed separately and identically. Disease recurrence at the surgical margin, ipsilateral hilum, and/or mediastinum was considered an LR. Recursive partitioning was used to build regression trees for the prediction of local recurrence-free survival (LRFS) from standard clinical and pathological factors. LRFS distributions were estimated with the Kaplan-Meier method.ResultsThe 1411 patients in the primary set had a 5-year LRFS rate of 77% (95% confidence interval [CI], 0.74-0.81), and the 889 patients in the validation set had a 5-year LRFS rate of 76% (95% CI, 0.72-0.80). The RPA of the primary data set identified 3 terminal nodes based on stage and histology. These nodes and their 5-year LRFS rates were as follows: (1) stage I/adenocarcinoma, 87% (95% CI, 0.83-0.90); (2) stage I/squamous or large cell, 72% (95% CI, 0.65-0.79); and (3) stage II-IIIA, 62% (95% CI, 0.55-0.69). The validation RPA identified 3 terminal nodes based on lymphovascular invasion (LVI) and stage: (1) no LVI/stage IA, 82% (95% CI, 0.76-0.88); (2) no LVI/stage IB-IIIA, 73% (95% CI, 0.69-0.80); and (3) LVI, 58% (95% CI, 0.47-0.69).ConclusionsThe risk of LR was similar in the primary and validation patient data sets. There was discordance between the 2 data sets regarding the clinical factors that best segregate patients into risk groups. To define subgroups at high risk of local recurrence (LR) after surgery for non–small cell lung cancer using a recursive partitioning analysis (RPA). This Institutional Review Board–approved study included patients who underwent upfront surgery for I-IIIA non–small cell lung cancer at Duke Cancer Institute (primary set) or at other participating institutions (validation set). The 2 data sets were analyzed separately and identically. Disease recurrence at the surgical margin, ipsilateral hilum, and/or mediastinum was considered an LR. Recursive partitioning was used to build regression trees for the prediction of local recurrence-free survival (LRFS) from standard clinical and pathological factors. LRFS distributions were estimated with the Kaplan-Meier method. The 1411 patients in the primary set had a 5-year LRFS rate of 77% (95% confidence interval [CI], 0.74-0.81), and the 889 patients in the validation set had a 5-year LRFS rate of 76% (95% CI, 0.72-0.80). The RPA of the primary data set identified 3 terminal nodes based on stage and histology. These nodes and their 5-year LRFS rates were as follows: (1) stage I/adenocarcinoma, 87% (95% CI, 0.83-0.90); (2) stage I/squamous or large cell, 72% (95% CI, 0.65-0.79); and (3) stage II-IIIA, 62% (95% CI, 0.55-0.69). The validation RPA identified 3 terminal nodes based on lymphovascular invasion (LVI) and stage: (1) no LVI/stage IA, 82% (95% CI, 0.76-0.88); (2) no LVI/stage IB-IIIA, 73% (95% CI, 0.69-0.80); and (3) LVI, 58% (95% CI, 0.47-0.69). The risk of LR was similar in the primary and validation patient data sets. There was discordance between the 2 data sets regarding the clinical factors that best segregate patients into risk groups." @default.
• W2014658918 created "2016-06-24" @default.
• W2014658918 creator A5006664559 @default.
• W2014658918 creator A5045431626 @default.
• W2014658918 creator A5056277456 @default.
• W2014658918 creator A5060888265 @default.
• W2014658918 creator A5080256711 @default.
• W2014658918 creator A5081655990 @default.
• W2014658918 creator A5085651347 @default.
• W2014658918 date "2013-10-01" @default.
• W2014658918 modified "2023-09-26" @default.
• W2014658918 title "Local recurrence after surgery for non–small cell lung cancer: A recursive partitioning analysis of multi-institutional data" @default.
• W2014658918 cites W1907932102 @default.
• W2014658918 cites W1965535010 @default.
• W2014658918 cites W1965662443 @default.
• W2014658918 cites W1973731306 @default.
• W2014658918 cites W1975727847 @default.
• W2014658918 cites W2002887395 @default.
• W2014658918 cites W2010200704 @default.
• W2014658918 cites W2017527202 @default.
• W2014658918 cites W2021329627 @default.
• W2014658918 cites W2032834679 @default.
• W2014658918 cites W2036882099 @default.
• W2014658918 cites W2057604474 @default.
• W2014658918 cites W2060473276 @default.
• W2014658918 cites W2078052487 @default.
• W2014658918 cites W2085074777 @default.
• W2014658918 cites W2087065324 @default.
• W2014658918 cites W2104543228 @default.
• W2014658918 cites W2104877698 @default.
• W2014658918 cites W2105365583 @default.
• W2014658918 cites W2148607233 @default.
• W2014658918 cites W2154951566 @default.
• W2014658918 cites W2158234609 @default.
• W2014658918 cites W2158734599 @default.
• W2014658918 cites W2158883606 @default.
• W2014658918 cites W2162670121 @default.
• W2014658918 cites W4241832356 @default.
• W2014658918 cites W4319718366 @default.
• W2014658918 doi "https://doi.org/10.1016/j.jtcvs.2013.05.041" @default.
• W2014658918 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23856204" @default.
• W2014658918 hasPublicationYear "2013" @default.
• W2014658918 type Work @default.
• W2014658918 sameAs 2014658918 @default.
• W2014658918 citedByCount "18" @default.
• W2014658918 countsByYear W20146589182014 @default.
• W2014658918 countsByYear W20146589182015 @default.
• W2014658918 countsByYear W20146589182016 @default.
• W2014658918 countsByYear W20146589182017 @default.
• W2014658918 countsByYear W20146589182018 @default.
• W2014658918 countsByYear W20146589182019 @default.
• W2014658918 countsByYear W20146589182020 @default.
• W2014658918 countsByYear W20146589182021 @default.
• W2014658918 countsByYear W20146589182022 @default.
• W2014658918 crossrefType "journal-article" @default.
• W2014658918 hasAuthorship W2014658918A5006664559 @default.
• W2014658918 hasAuthorship W2014658918A5045431626 @default.
• W2014658918 hasAuthorship W2014658918A5056277456 @default.
• W2014658918 hasAuthorship W2014658918A5060888265 @default.
• W2014658918 hasAuthorship W2014658918A5080256711 @default.
• W2014658918 hasAuthorship W2014658918A5081655990 @default.
• W2014658918 hasAuthorship W2014658918A5085651347 @default.
• W2014658918 hasBestOaLocation W20146589181 @default.
• W2014658918 hasConcept C121608353 @default.
• W2014658918 hasConcept C126322002 @default.
• W2014658918 hasConcept C137345334 @default.
• W2014658918 hasConcept C141071460 @default.
• W2014658918 hasConcept C143998085 @default.
• W2014658918 hasConcept C146357865 @default.
• W2014658918 hasConcept C151730666 @default.
• W2014658918 hasConcept C2776256026 @default.
• W2014658918 hasConcept C2778740770 @default.
• W2014658918 hasConcept C2779013556 @default.
• W2014658918 hasConcept C44249647 @default.
• W2014658918 hasConcept C50382708 @default.
• W2014658918 hasConcept C71924100 @default.
• W2014658918 hasConcept C86803240 @default.
• W2014658918 hasConceptScore W2014658918C121608353 @default.
• W2014658918 hasConceptScore W2014658918C126322002 @default.
• W2014658918 hasConceptScore W2014658918C137345334 @default.
• W2014658918 hasConceptScore W2014658918C141071460 @default.
• W2014658918 hasConceptScore W2014658918C143998085 @default.
• W2014658918 hasConceptScore W2014658918C146357865 @default.
• W2014658918 hasConceptScore W2014658918C151730666 @default.
• W2014658918 hasConceptScore W2014658918C2776256026 @default.
• W2014658918 hasConceptScore W2014658918C2778740770 @default.
• W2014658918 hasConceptScore W2014658918C2779013556 @default.
• W2014658918 hasConceptScore W2014658918C44249647 @default.
• W2014658918 hasConceptScore W2014658918C50382708 @default.
• W2014658918 hasConceptScore W2014658918C71924100 @default.
• W2014658918 hasConceptScore W2014658918C86803240 @default.
• W2014658918 hasIssue "4" @default.
• W2014658918 hasLocation W20146589181 @default.
• W2014658918 hasLocation W20146589182 @default.
• W2014658918 hasLocation W20146589183 @default.
• W2014658918 hasOpenAccess W2014658918 @default.
• W2014658918 hasPrimaryLocation W20146589181 @default.
• W2014658918 hasRelatedWork W2003938723 @default.

• next