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- W2014662502 abstract "Integrin-mediated adhesion to the extracellular matrix plays an important role in regulating cell survival and proliferation. There is now increasing evidence that integrins activate shared as well as subgroup-specific signaling pathways. The signals from these adhesion receptors are integrated with those originating from growth factor and cytokine receptors in order to organize the cytoskeleton, stimulate mitogen-activated protein kinase cascades, and regulate immediate early gene expression. The repertoire of integrins and composition of the extracellular matrix appear to dictate whether a cell will survive, proliferate or exit the cell cycle and differentiate in response to soluble factors." @default.
- W2014662502 created "2016-06-24" @default.
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- W2014662502 date "1997-10-01" @default.
- W2014662502 modified "2023-10-14" @default.
- W2014662502 title "Integrin signaling: specificity and control of cell survival and cell cycle progression" @default.
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- W2014662502 doi "https://doi.org/10.1016/s0955-0674(97)80123-8" @default.
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