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- W2014665756 abstract "Abstract A fluorescent chiral molecular micelle (FCMM), poly (sodium N ‐undecanoyl‐ L ‐phenylalaninate) (poly‐ L ‐SUF), was developed as a chiral selector for enantiomeric recognition and determination of enantiomeric composition of four fluorescent and four nonfluorescent chiral molecules by use of steady‐state fluorescence spectroscopy. The influence of FCMM concentration, buffer pH and complexation medium on FCMM‐analyte host–guest complexation, and the emission spectral properties of the resulting complexes were investigated. The chiral interactions of the analytes,1,1′‐binaphthyl‐2,2′‐diamine, 1‐(9‐anthryl)‐2,2,2‐trifluoroethanol, propranolol, naproxen, chloromethyl menthyl ether (CME), citramalic acid, tartaric acid, and limonene (LIM), in the presence of poly‐ L ‐SUF were based on diastereomeric complex formation. The figures of merit obtained from the partial‐least‐squares regression modeling of the calibration samples suggested good prediction ability for the validation of six of the eight chiral analytes. Better host–guest complexation of the more hydrophobic molecules, CME and LIM, were obtained in methanol/water mixtures, resulting in better predictability of the regression models. Prediction ability of the models was evaluated by use of the root‐mean‐square percent relative error ( RMS%RE ) and was found to range from 1.77 to 15.80% (buffer), 1.26 to 7.95% (25:75 methanol/water), and 1.21 to 4.28% (75:25 methanol/water). Chirality, 2009. © 2008 Wiley‐Liss, Inc." @default.
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- W2014665756 date "2008-05-29" @default.
- W2014665756 modified "2023-10-07" @default.
- W2014665756 title "A versatile chiral selector for determination of enantiomeric composition of fluorescent and nonfluorescent chiral molecules using steady‐state fluorescence spectroscopy" @default.
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- W2014665756 doi "https://doi.org/10.1002/chir.20580" @default.
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