FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014667116> ?p ?o ?g. }

• W2014667116 endingPage "3814" @default.
• W2014667116 startingPage "3807" @default.
• W2014667116 abstract "A new member of polyhydroxyalkanoates (PHA) family, namely, a terpolyester abbreviated as PHBVHHx consisting of 3-hydroxybutyrate (HB), 3-hydroxyvalerate (HV) and 3-hydroxyhexanoate (HHx) that can be produced by recombinant microorganisms, was found to have proper thermo- and mechanical properties for possible skin tissue engineering, as demonstrated by its strong ability to support the growth of human keratinocyte cell line HaCaT. In this study, HaCaT cells showed the strongest viability and the highest growth activity on PHBVHHx film compared with PLA, PHB, PHBV, PHBHHx and P3HB4HB, even the tissue culture plates were grown with less HaCaT cells compared with that on PHBVHHx. To understand its superior biocompatibility, PHBVHHx nanoparticles ranging from 200 to 350nm were prepared. It was found that the nanoparticles could increase the cellular activities by stimulating a rapid increase of cytosolic calcium influx in HaCaT cells, leading to enhanced cell growth. At the same time, 3-hydroxybutyrate (HB), a degradation product and the main component of PHBVHHx, was also shown to promote HaCaT proliferation. Morphologically, under the same preparation conditions, PHBVHHx film showed the most obvious surface roughness under atomic force microscopy (AFM), accompanied by the lowest surface energy compared with all other well studied biopolymers tested above. These results explained the superior ability for PHBVHHx to grow skin HaCaT cells. Therefore, PHBVHHx possesses the suitability to be developed into a skin tissue-engineered material." @default.
• W2014667116 created "2016-06-24" @default.
• W2014667116 creator A5003180460 @default.
• W2014667116 creator A5017175637 @default.
• W2014667116 creator A5047351210 @default.
• W2014667116 date "2008-10-01" @default.
• W2014667116 modified "2023-10-17" @default.
• W2014667116 title "Interactions between a poly(3-hydroxybutyrate-co-3-hydroxyvalerate-co-3-hydroxyhexanoate) terpolyester and human keratinocytes" @default.
• W2014667116 cites W1892444139 @default.
• W2014667116 cites W1964086098 @default.
• W2014667116 cites W1964327951 @default.
• W2014667116 cites W1969334945 @default.
• W2014667116 cites W2001770837 @default.
• W2014667116 cites W2005664272 @default.
• W2014667116 cites W2006227180 @default.
• W2014667116 cites W2015575124 @default.
• W2014667116 cites W2028269873 @default.
• W2014667116 cites W2035543265 @default.
• W2014667116 cites W2039517105 @default.
• W2014667116 cites W2042207484 @default.
• W2014667116 cites W2048493287 @default.
• W2014667116 cites W2051474403 @default.
• W2014667116 cites W2052910159 @default.
• W2014667116 cites W2056023823 @default.
• W2014667116 cites W2056670956 @default.
• W2014667116 cites W2056778275 @default.
• W2014667116 cites W2059718597 @default.
• W2014667116 cites W2060494531 @default.
• W2014667116 cites W2064522198 @default.
• W2014667116 cites W2074835807 @default.
• W2014667116 cites W2078497186 @default.
• W2014667116 cites W2082723727 @default.
• W2014667116 cites W2092499238 @default.
• W2014667116 cites W2094075470 @default.
• W2014667116 cites W2103984819 @default.
• W2014667116 cites W2107233558 @default.
• W2014667116 cites W2122364241 @default.
• W2014667116 cites W2131082021 @default.
• W2014667116 cites W2143464311 @default.
• W2014667116 cites W2144744614 @default.
• W2014667116 cites W2160669887 @default.
• W2014667116 cites W4242174061 @default.
• W2014667116 cites W4250776470 @default.
• W2014667116 doi "https://doi.org/10.1016/j.biomaterials.2008.06.008" @default.
• W2014667116 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18597841" @default.
• W2014667116 hasPublicationYear "2008" @default.
• W2014667116 type Work @default.
• W2014667116 sameAs 2014667116 @default.
• W2014667116 citedByCount "79" @default.
• W2014667116 countsByYear W20146671162012 @default.
• W2014667116 countsByYear W20146671162013 @default.
• W2014667116 countsByYear W20146671162014 @default.
• W2014667116 countsByYear W20146671162015 @default.
• W2014667116 countsByYear W20146671162016 @default.
• W2014667116 countsByYear W20146671162017 @default.
• W2014667116 countsByYear W20146671162018 @default.
• W2014667116 countsByYear W20146671162019 @default.
• W2014667116 countsByYear W20146671162020 @default.
• W2014667116 countsByYear W20146671162021 @default.
• W2014667116 countsByYear W20146671162022 @default.
• W2014667116 countsByYear W20146671162023 @default.
• W2014667116 crossrefType "journal-article" @default.
• W2014667116 hasAuthorship W2014667116A5003180460 @default.
• W2014667116 hasAuthorship W2014667116A5017175637 @default.
• W2014667116 hasAuthorship W2014667116A5047351210 @default.
• W2014667116 hasConcept C118995209 @default.
• W2014667116 hasConcept C12554922 @default.
• W2014667116 hasConcept C127413603 @default.
• W2014667116 hasConcept C136229726 @default.
• W2014667116 hasConcept C1491633281 @default.
• W2014667116 hasConcept C155672457 @default.
• W2014667116 hasConcept C171250308 @default.
• W2014667116 hasConcept C185592680 @default.
• W2014667116 hasConcept C191897082 @default.
• W2014667116 hasConcept C192562407 @default.
• W2014667116 hasConcept C202751555 @default.
• W2014667116 hasConcept C2777074287 @default.
• W2014667116 hasConcept C2777230088 @default.
• W2014667116 hasConcept C42360764 @default.
• W2014667116 hasConcept C49892992 @default.
• W2014667116 hasConcept C523546767 @default.
• W2014667116 hasConcept C53227056 @default.
• W2014667116 hasConcept C54355233 @default.
• W2014667116 hasConcept C55493867 @default.
• W2014667116 hasConcept C62112901 @default.
• W2014667116 hasConcept C71924100 @default.
• W2014667116 hasConcept C73447357 @default.
• W2014667116 hasConcept C81885089 @default.
• W2014667116 hasConcept C86803240 @default.
• W2014667116 hasConcept C95444343 @default.
• W2014667116 hasConceptScore W2014667116C118995209 @default.
• W2014667116 hasConceptScore W2014667116C12554922 @default.
• W2014667116 hasConceptScore W2014667116C127413603 @default.
• W2014667116 hasConceptScore W2014667116C136229726 @default.
• W2014667116 hasConceptScore W2014667116C1491633281 @default.
• W2014667116 hasConceptScore W2014667116C155672457 @default.
• W2014667116 hasConceptScore W2014667116C171250308 @default.
• W2014667116 hasConceptScore W2014667116C185592680 @default.

• next