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- W2014668128 abstract "✓ Specimens of 16 human brain tumors were studied by the indirect fluorescent-antibody technique to reveal the localization of the particular cerebroprotein found in strikingly increased amounts in human glial tumors as well as in the brain of a patient with Tay-Sachs disease. The cerebro-protein fraction named “10B” by Bogoch was found exclusively in reactive astrocytes, both in astrocytomas and in glioblastomas multiforme. Both the cytoplasm and the cell processes fluoresced upon exposure to antiserum to the “10B” proteins of Tay-Sachs disease. Fluorescence of fibrillary astrocytes located in white matter at some distance from a tumor might be related to discrete edematous changes or constitute an early step in the transition of normal glia to reactive or neoplastic astrocytes. There was no such staining of frankly neoplastic cells or of normal ganglion cells." @default.
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- W2014668128 title "Demonstration of an astrocyte-specific cerebroprotein by an immunofluorescence study of human brain tumors" @default.
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