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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014668728> ?p ?o ?g. }

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• W2014668728 abstract "Cytotoxic artemisinin derivatives have been synthesized by a modular approach of “artemisinin + linker + lipophilic alkyl carbon chain”. A strong correlation between the length of the carbon chains and the cytotoxicities against human hepatocellular carcinoma (HepG2) was revealed. Notably, compared with artemisinin (IC50 = 97 μM), up to 200-fold more potent cytotoxicity (IC50 = 0.46 μM) could be achieved by attachment of a C14H29 carbon chain to artemisinin via an amide linker." @default.
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• W2014668728 date "2005-03-18" @default.
• W2014668728 modified "2023-10-01" @default.
• W2014668728 title "Synthesis and Cytotoxicity Studies of Artemisinin Derivatives Containing Lipophilic Alkyl Carbon Chains" @default.
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• W2014668728 doi "https://doi.org/10.1021/ol050230o" @default.
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