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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014672110> ?p ?o ?g. }

• W2014672110 endingPage "346" @default.
• W2014672110 startingPage "339" @default.
• W2014672110 abstract "The complement (C) plays an important role in many acute inflammatory processes. C3a is an inflammatory polypeptide named anaphylatoxin, generated during C activation and which acts through a specific receptor C3aR. In this study, we demonstrated that the epithelial cell line ECV 304 constitutively expressed C3aR (by flow cytometry and immunofluorescence) and that binding of purified C3a to epithelial cells resulted in a time- and dose-dependent upregulation of interleukin-8 (IL-8). Pre-treatment of ECV 304 with pertussis toxin inhibited IL-8 response induced by C3a, indicating that the action of C3a was mediated by a G protein coupled pathway." @default.
• W2014672110 created "2016-06-24" @default.
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• W2014672110 date "2001-01-05" @default.
• W2014672110 modified "2023-10-10" @default.
• W2014672110 title "C3A binds to the seven transmembrane anaphylatoxin receptor expressed by epithelial cells and triggers the production of IL-8" @default.
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• W2014672110 doi "https://doi.org/10.1016/s0014-5793(00)02320-6" @default.
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