Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014672384> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W2014672384 endingPage "593" @default.
- W2014672384 startingPage "589" @default.
- W2014672384 abstract "The purpose of the present study is twofold, firstly to investigate the effects of alpha-human atrial natriuretic polypeptide (alpha-hANP) on norepinephrine overflow from sympathetic nerve endings, and secondly to compare vascular responsiveness in perfused mesenteric preparations in spontaneously hypertensive rats (SHR, Okamoto and Aoki, 7-9 weeks old) and a cohort of Wistar Kyoto rats (WKY). In preliminary studies using normotensive Wistar rats, the pressor responses to electrical nerve stimulation or exogenous norepinephrine application were inhibited by alpha-hANP. Norepinephrine overflow was also suppressed by alpha-hANP, during nerve stimulation. The pressor responses and norepinephrine overflow during nerve stimulation were significantly greater in SHR than in WKY rats. The inhibitory effect of alpha-hANP on these responses was reduced in SHR. These results indicate that alpha-hANP could affect both pre- and post-synaptic sites of the resistance vessels. Further, the reduced inhibition of pressor responses and norepinephrine overflow by alpha-hANP in SHR suggests an insufficient regulation of adrenergic transmission by alpha-hANP in hypertension." @default.
- W2014672384 created "2016-06-24" @default.
- W2014672384 creator A5019186366 @default.
- W2014672384 creator A5042385500 @default.
- W2014672384 creator A5072699921 @default.
- W2014672384 creator A5081699525 @default.
- W2014672384 date "1987-01-01" @default.
- W2014672384 modified "2023-09-26" @default.
- W2014672384 title "Inhibitory action on alpha-human atrial natriuretic polypeptide on vascular adrenergic neurotransmission is attenuated in spontaneously hypertensive rats." @default.
- W2014672384 doi "https://doi.org/10.1253/jcj.51.589" @default.
- W2014672384 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3041065" @default.
- W2014672384 hasPublicationYear "1987" @default.
- W2014672384 type Work @default.
- W2014672384 sameAs 2014672384 @default.
- W2014672384 citedByCount "7" @default.
- W2014672384 crossrefType "journal-article" @default.
- W2014672384 hasAuthorship W2014672384A5019186366 @default.
- W2014672384 hasAuthorship W2014672384A5042385500 @default.
- W2014672384 hasAuthorship W2014672384A5072699921 @default.
- W2014672384 hasAuthorship W2014672384A5081699525 @default.
- W2014672384 hasBestOaLocation W20146723841 @default.
- W2014672384 hasConcept C126322002 @default.
- W2014672384 hasConcept C134018914 @default.
- W2014672384 hasConcept C158453852 @default.
- W2014672384 hasConcept C159110408 @default.
- W2014672384 hasConcept C170493617 @default.
- W2014672384 hasConcept C17077164 @default.
- W2014672384 hasConcept C185592680 @default.
- W2014672384 hasConcept C200170125 @default.
- W2014672384 hasConcept C24998067 @default.
- W2014672384 hasConcept C2775944032 @default.
- W2014672384 hasConcept C2778514916 @default.
- W2014672384 hasConcept C3018430268 @default.
- W2014672384 hasConcept C40465926 @default.
- W2014672384 hasConcept C49453240 @default.
- W2014672384 hasConcept C513476851 @default.
- W2014672384 hasConcept C64943373 @default.
- W2014672384 hasConcept C71924100 @default.
- W2014672384 hasConceptScore W2014672384C126322002 @default.
- W2014672384 hasConceptScore W2014672384C134018914 @default.
- W2014672384 hasConceptScore W2014672384C158453852 @default.
- W2014672384 hasConceptScore W2014672384C159110408 @default.
- W2014672384 hasConceptScore W2014672384C170493617 @default.
- W2014672384 hasConceptScore W2014672384C17077164 @default.
- W2014672384 hasConceptScore W2014672384C185592680 @default.
- W2014672384 hasConceptScore W2014672384C200170125 @default.
- W2014672384 hasConceptScore W2014672384C24998067 @default.
- W2014672384 hasConceptScore W2014672384C2775944032 @default.
- W2014672384 hasConceptScore W2014672384C2778514916 @default.
- W2014672384 hasConceptScore W2014672384C3018430268 @default.
- W2014672384 hasConceptScore W2014672384C40465926 @default.
- W2014672384 hasConceptScore W2014672384C49453240 @default.
- W2014672384 hasConceptScore W2014672384C513476851 @default.
- W2014672384 hasConceptScore W2014672384C64943373 @default.
- W2014672384 hasConceptScore W2014672384C71924100 @default.
- W2014672384 hasIssue "5" @default.
- W2014672384 hasLocation W20146723841 @default.
- W2014672384 hasLocation W20146723842 @default.
- W2014672384 hasOpenAccess W2014672384 @default.
- W2014672384 hasPrimaryLocation W20146723841 @default.
- W2014672384 hasRelatedWork W1835699834 @default.
- W2014672384 hasRelatedWork W1974809200 @default.
- W2014672384 hasRelatedWork W1997653766 @default.
- W2014672384 hasRelatedWork W2014672384 @default.
- W2014672384 hasRelatedWork W2052453588 @default.
- W2014672384 hasRelatedWork W2062851024 @default.
- W2014672384 hasRelatedWork W2078987736 @default.
- W2014672384 hasRelatedWork W2405946248 @default.
- W2014672384 hasRelatedWork W349556749 @default.
- W2014672384 hasRelatedWork W4243387032 @default.
- W2014672384 hasVolume "51" @default.
- W2014672384 isParatext "false" @default.
- W2014672384 isRetracted "false" @default.
- W2014672384 magId "2014672384" @default.
- W2014672384 workType "article" @default.