Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014677549> ?p ?o ?g. }
- W2014677549 abstract "The aim of this study is to investigate the effect of macroscopic grooves on bone formation in vivo and differentiation of human mesenchymal stem cells (hMSCs) in vitro.The effects of macroscopic grooves on titanium alloy implants and disks were tested in rabbit tibiae and cultured hMSCs. The bone-to-implant contact (BIC) and bone area were evaluated in rabbit tibiae at 6 and 24 weeks after implant insertion. Osteoblastic differentiation was assessed by alkaline phosphatase (ALP) activity and real-time reverse-transcription polymerase chain reaction (RT-PCR) on days 7, 14, and 21. All values were statically analyzed.BIC and bone area inside the grooves were significantly higher than those of control implants (P < 0.05). ALP activity was significantly higher for titanium disks with macroscopic grooves than without grooves on day 14 (P < 0.05). Real-time RT-PCR showed that the expression of osteogenic genes was significantly higher for disks with grooves on day 7 (P < 0.01).Macroscopic grooves accelerate osteoblastic differentiation in vitro and stimulate direct bone growth and deposition within the grooves in vivo." @default.
- W2014677549 created "2016-06-24" @default.
- W2014677549 creator A5002399171 @default.
- W2014677549 creator A5007385692 @default.
- W2014677549 creator A5023089330 @default.
- W2014677549 creator A5069680432 @default.
- W2014677549 date "2015-04-25" @default.
- W2014677549 modified "2023-10-12" @default.
- W2014677549 title "Effect of Macroscopic Grooves on Bone Formation and Osteoblastic Differentiation" @default.
- W2014677549 cites W1577118233 @default.
- W2014677549 cites W1970278573 @default.
- W2014677549 cites W1981619507 @default.
- W2014677549 cites W1985966495 @default.
- W2014677549 cites W1990414407 @default.
- W2014677549 cites W2026988630 @default.
- W2014677549 cites W2032524331 @default.
- W2014677549 cites W2061802170 @default.
- W2014677549 cites W2079007837 @default.
- W2014677549 cites W2085813125 @default.
- W2014677549 cites W2104344518 @default.
- W2014677549 cites W2108244474 @default.
- W2014677549 cites W2114524033 @default.
- W2014677549 cites W2115444100 @default.
- W2014677549 cites W2117620360 @default.
- W2014677549 cites W2117841258 @default.
- W2014677549 cites W2119966149 @default.
- W2014677549 cites W2132309525 @default.
- W2014677549 cites W2133567409 @default.
- W2014677549 cites W2151005356 @default.
- W2014677549 cites W2152321517 @default.
- W2014677549 cites W2152788626 @default.
- W2014677549 cites W2159210886 @default.
- W2014677549 cites W2167112719 @default.
- W2014677549 cites W4376848829 @default.
- W2014677549 doi "https://doi.org/10.1097/id.0000000000000257" @default.
- W2014677549 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25923016" @default.
- W2014677549 hasPublicationYear "2015" @default.
- W2014677549 type Work @default.
- W2014677549 sameAs 2014677549 @default.
- W2014677549 citedByCount "2" @default.
- W2014677549 countsByYear W20146775492021 @default.
- W2014677549 countsByYear W20146775492022 @default.
- W2014677549 crossrefType "journal-article" @default.
- W2014677549 hasAuthorship W2014677549A5002399171 @default.
- W2014677549 hasAuthorship W2014677549A5007385692 @default.
- W2014677549 hasAuthorship W2014677549A5023089330 @default.
- W2014677549 hasAuthorship W2014677549A5069680432 @default.
- W2014677549 hasBestOaLocation W20146775492 @default.
- W2014677549 hasConcept C105702510 @default.
- W2014677549 hasConcept C134018914 @default.
- W2014677549 hasConcept C136229726 @default.
- W2014677549 hasConcept C141071460 @default.
- W2014677549 hasConcept C150903083 @default.
- W2014677549 hasConcept C160160445 @default.
- W2014677549 hasConcept C178790620 @default.
- W2014677549 hasConcept C181199279 @default.
- W2014677549 hasConcept C185592680 @default.
- W2014677549 hasConcept C198826908 @default.
- W2014677549 hasConcept C202751555 @default.
- W2014677549 hasConcept C207001950 @default.
- W2014677549 hasConcept C2781411149 @default.
- W2014677549 hasConcept C2993291840 @default.
- W2014677549 hasConcept C506065880 @default.
- W2014677549 hasConcept C55493867 @default.
- W2014677549 hasConcept C71924100 @default.
- W2014677549 hasConcept C86803240 @default.
- W2014677549 hasConcept C95444343 @default.
- W2014677549 hasConceptScore W2014677549C105702510 @default.
- W2014677549 hasConceptScore W2014677549C134018914 @default.
- W2014677549 hasConceptScore W2014677549C136229726 @default.
- W2014677549 hasConceptScore W2014677549C141071460 @default.
- W2014677549 hasConceptScore W2014677549C150903083 @default.
- W2014677549 hasConceptScore W2014677549C160160445 @default.
- W2014677549 hasConceptScore W2014677549C178790620 @default.
- W2014677549 hasConceptScore W2014677549C181199279 @default.
- W2014677549 hasConceptScore W2014677549C185592680 @default.
- W2014677549 hasConceptScore W2014677549C198826908 @default.
- W2014677549 hasConceptScore W2014677549C202751555 @default.
- W2014677549 hasConceptScore W2014677549C207001950 @default.
- W2014677549 hasConceptScore W2014677549C2781411149 @default.
- W2014677549 hasConceptScore W2014677549C2993291840 @default.
- W2014677549 hasConceptScore W2014677549C506065880 @default.
- W2014677549 hasConceptScore W2014677549C55493867 @default.
- W2014677549 hasConceptScore W2014677549C71924100 @default.
- W2014677549 hasConceptScore W2014677549C86803240 @default.
- W2014677549 hasConceptScore W2014677549C95444343 @default.
- W2014677549 hasLocation W20146775491 @default.
- W2014677549 hasLocation W20146775492 @default.
- W2014677549 hasLocation W20146775493 @default.
- W2014677549 hasOpenAccess W2014677549 @default.
- W2014677549 hasPrimaryLocation W20146775491 @default.
- W2014677549 hasRelatedWork W1924092459 @default.
- W2014677549 hasRelatedWork W2015148133 @default.
- W2014677549 hasRelatedWork W2023654614 @default.
- W2014677549 hasRelatedWork W2050042332 @default.
- W2014677549 hasRelatedWork W2075883544 @default.
- W2014677549 hasRelatedWork W2148676064 @default.
- W2014677549 hasRelatedWork W2350278514 @default.
- W2014677549 hasRelatedWork W3042682851 @default.
- W2014677549 hasRelatedWork W4255217905 @default.