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• W2014684062 abstract "An experimental drug, 1-(1,3-benzodioxol-5-ylcarbonyl)piperidine, that facilitates glutamatergic transmission in brain after systemic administration was tested for its effects on the induction of long-term potentiation in the hippocampus of rats. Intraperitoneal injections of the drug markedly increased the degree and duration of long-term potentiation; similar results were obtained with an analogue of 1-(1,3-benzodioxol-5-ylcarbonyl)piperidine that was also found to improve retention of memory in a radial maze task and in an odor-matching problem. These results define tools for enhancing long-term potentiation in vivo and confirm an important prediction from the hypothesis that long-term potentiation is a substrate of memory." @default.
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• W2014684062 date "1994-11-08" @default.
• W2014684062 modified "2023-10-04" @default.
• W2014684062 title "Centrally active modulators of glutamate receptors facilitate the induction of long-term potentiation in vivo." @default.
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• W2014684062 doi "https://doi.org/10.1073/pnas.91.23.11158" @default.
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