FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014688006> ?p ?o ?g. }

• W2014688006 endingPage "477" @default.
• W2014688006 startingPage "468" @default.
• W2014688006 abstract "A bstract : Many factors during fetal life and early infancy have been found to affect the development of immune responses in animals. This study investigated whether acute exposure of the fetal monkey to high levels of corticosteroids would also have a lingering effect on the expression of immune responses still manifest postpartum in yearling juveniles. One month prior to parturition, pregnant rhesus monkeys were administered dexamethasone for two days. Lymphocyte proliferative responses to mitogen were then examined in their offspring when they were between 1.0‐1.5 years of age. In addition, cell sensitivity to corticosteroid feedback was assessed by testing the ability of a gradation of cortisol doses to inhibit proliferation. Monkeys generated from dexamethasone‐treated pregnancies tended to have lower responses to concanavalin A. Further, their cells were less sensitive to in vitro incubation with cortisol, suggesting that elevated adrenal activity in vivo had downregulated hormone receptors on their cells. These findings concur with the view that steroidal hormones in utero can influence the fetal immune system, resulting in prolonged effects on immune responses after birth. The similarity of the dexamethasone condition to the clinical treatment used in obstetrical practice raises a potential concern about the widespread antenatal exposure of premature infants to steroidal drugs." @default.
• W2014688006 created "2016-06-24" @default.
• W2014688006 creator A5015543369 @default.
• W2014688006 creator A5023136649 @default.
• W2014688006 date "2000-01-01" @default.
• W2014688006 modified "2023-09-23" @default.
• W2014688006 title "Prenatal Influences on Neuroimmune Set Points in Infancy" @default.
• W2014688006 cites W1847512305 @default.
• W2014688006 cites W1984331377 @default.
• W2014688006 cites W2004491405 @default.
• W2014688006 cites W2005462099 @default.
• W2014688006 cites W2007170162 @default.
• W2014688006 cites W2008842534 @default.
• W2014688006 cites W2009228159 @default.
• W2014688006 cites W2010045713 @default.
• W2014688006 cites W2027985523 @default.
• W2014688006 cites W2031366883 @default.
• W2014688006 cites W2035489261 @default.
• W2014688006 cites W2035879915 @default.
• W2014688006 cites W2039801588 @default.
• W2014688006 cites W2041713234 @default.
• W2014688006 cites W2044683687 @default.
• W2014688006 cites W2047844446 @default.
• W2014688006 cites W2049530156 @default.
• W2014688006 cites W2060800424 @default.
• W2014688006 cites W2083937016 @default.
• W2014688006 cites W2092684842 @default.
• W2014688006 cites W2262882541 @default.
• W2014688006 cites W2314701743 @default.
• W2014688006 cites W2410741894 @default.
• W2014688006 doi "https://doi.org/10.1111/j.1749-6632.2000.tb05411.x" @default.
• W2014688006 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11268374" @default.
• W2014688006 hasPublicationYear "2000" @default.
• W2014688006 type Work @default.
• W2014688006 sameAs 2014688006 @default.
• W2014688006 citedByCount "54" @default.
• W2014688006 countsByYear W20146880062012 @default.
• W2014688006 countsByYear W20146880062013 @default.
• W2014688006 countsByYear W20146880062014 @default.
• W2014688006 countsByYear W20146880062015 @default.
• W2014688006 countsByYear W20146880062016 @default.
• W2014688006 countsByYear W20146880062017 @default.
• W2014688006 countsByYear W20146880062019 @default.
• W2014688006 countsByYear W20146880062022 @default.
• W2014688006 countsByYear W20146880062023 @default.
• W2014688006 crossrefType "journal-article" @default.
• W2014688006 hasAuthorship W2014688006A5015543369 @default.
• W2014688006 hasAuthorship W2014688006A5023136649 @default.
• W2014688006 hasConcept C112672928 @default.
• W2014688006 hasConcept C126322002 @default.
• W2014688006 hasConcept C134018914 @default.
• W2014688006 hasConcept C172680121 @default.
• W2014688006 hasConcept C19869320 @default.
• W2014688006 hasConcept C201614185 @default.
• W2014688006 hasConcept C202751555 @default.
• W2014688006 hasConcept C203014093 @default.
• W2014688006 hasConcept C2777761686 @default.
• W2014688006 hasConcept C2779234561 @default.
• W2014688006 hasConcept C2780401358 @default.
• W2014688006 hasConcept C2780841215 @default.
• W2014688006 hasConcept C42407357 @default.
• W2014688006 hasConcept C54355233 @default.
• W2014688006 hasConcept C55493867 @default.
• W2014688006 hasConcept C59493245 @default.
• W2014688006 hasConcept C71315377 @default.
• W2014688006 hasConcept C71924100 @default.
• W2014688006 hasConcept C86803240 @default.
• W2014688006 hasConcept C8891405 @default.
• W2014688006 hasConceptScore W2014688006C112672928 @default.
• W2014688006 hasConceptScore W2014688006C126322002 @default.
• W2014688006 hasConceptScore W2014688006C134018914 @default.
• W2014688006 hasConceptScore W2014688006C172680121 @default.
• W2014688006 hasConceptScore W2014688006C19869320 @default.
• W2014688006 hasConceptScore W2014688006C201614185 @default.
• W2014688006 hasConceptScore W2014688006C202751555 @default.
• W2014688006 hasConceptScore W2014688006C203014093 @default.
• W2014688006 hasConceptScore W2014688006C2777761686 @default.
• W2014688006 hasConceptScore W2014688006C2779234561 @default.
• W2014688006 hasConceptScore W2014688006C2780401358 @default.
• W2014688006 hasConceptScore W2014688006C2780841215 @default.
• W2014688006 hasConceptScore W2014688006C42407357 @default.
• W2014688006 hasConceptScore W2014688006C54355233 @default.
• W2014688006 hasConceptScore W2014688006C55493867 @default.
• W2014688006 hasConceptScore W2014688006C59493245 @default.
• W2014688006 hasConceptScore W2014688006C71315377 @default.
• W2014688006 hasConceptScore W2014688006C71924100 @default.
• W2014688006 hasConceptScore W2014688006C86803240 @default.
• W2014688006 hasConceptScore W2014688006C8891405 @default.
• W2014688006 hasIssue "1" @default.
• W2014688006 hasLocation W20146880061 @default.
• W2014688006 hasLocation W20146880062 @default.
• W2014688006 hasOpenAccess W2014688006 @default.
• W2014688006 hasPrimaryLocation W20146880061 @default.
• W2014688006 hasRelatedWork W1976035881 @default.
• W2014688006 hasRelatedWork W2019289923 @default.
• W2014688006 hasRelatedWork W2022187101 @default.
• W2014688006 hasRelatedWork W2034583712 @default.
• W2014688006 hasRelatedWork W2066225521 @default.

• next