FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014690503> ?p ?o ?g. }

• W2014690503 endingPage "665" @default.
• W2014690503 startingPage "661" @default.
• W2014690503 abstract "In patients with acutely symptomatic but nonruptured abdominal aortic aneurysm (AAA), emergent repair is associated with an increased mortality rate as compared with semi-elective repair. Previous results have shown that ruptured but not asymptomatic AAA repair is associated with intense thrombin generation and inhibition of systemic fibrinolysis. The purpose of this study was to determine whether circulating markers of coagulation and fibrinolysis may be used to distinguish acutely symptomatic nonruptured and ruptured AAA.A prospective study was performed of 44 patients who underwent emergency AAA repair for suspected rupture. Platelet count, fibrinogen level, prothrombin time, activated partial thromboplastin time, tissue plasminogen activator (t-PA) activity, plasminogen activator inhibitor (PAI) activity, prothrombin fragment (PF) 1+2 level, and D dimer level were measured before surgery.When compared with ruptured AAAs (n = 37), acutely symptomatic nonruptured AAAs (n = 7) were associated with increased fibrinogen level (P =.033), reduced activated partial thromboplastin time (P =.043), increased t-PA activity (P =.023), reduced PAI activity (P =.005), reduced PF 1+2 level (P =.001), and reduced D dimer level (P =.005; all P values determined with Mann-Whitney test). The differences in t-PA activity (P =.01), PAI activity (P =.004), and PF 1+2 level (P =.01) persisted in patients whose conditions were normotensive. In all patients, a PF 1+2 level of greater than or equal to 2.5 nmol/L was associated with a sensitivity, specificity, and positive and negative predictive value for rupture of 89%, 86%, 97%, and 60%, respectively. In patients whose conditions were normotensive, PAI activity of greater than or equal to 16 AU/mL was associated with a sensitivity, specificity, and positive and negative predictive value of 83%, 100%, 100%, and 88%, respectively.These data show that acutely symptomatic nonruptured AAA is associated with increased systemic fibrinolysis (caused by reduced fibrinolytic inhibition) and reduced thrombin generation as compared with rupture. Preoperative hemostatic markers, particularly PF 1+2 level and PAI activity, may distinguish acutely symptomatic nonruptured from ruptured AAA." @default.
• W2014690503 created "2016-06-24" @default.
• W2014690503 creator A5027703697 @default.
• W2014690503 creator A5033903155 @default.
• W2014690503 creator A5037767298 @default.
• W2014690503 creator A5042777389 @default.
• W2014690503 date "2002-04-01" @default.
• W2014690503 modified "2023-09-27" @default.
• W2014690503 title "Hemostatic markers before operation in patients with acutely symptomatic nonruptured and ruptured infrarenal abdominal aortic aneurysm" @default.
• W2014690503 cites W1968368894 @default.
• W2014690503 cites W1970189888 @default.
• W2014690503 cites W1971257600 @default.
• W2014690503 cites W1983742840 @default.
• W2014690503 cites W2002027433 @default.
• W2014690503 cites W2032360995 @default.
• W2014690503 cites W2036277693 @default.
• W2014690503 cites W2039238472 @default.
• W2014690503 cites W2048078727 @default.
• W2014690503 cites W2067779631 @default.
• W2014690503 cites W2081060841 @default.
• W2014690503 cites W2083256267 @default.
• W2014690503 cites W2086349134 @default.
• W2014690503 cites W2092952849 @default.
• W2014690503 cites W2105364538 @default.
• W2014690503 cites W2115415548 @default.
• W2014690503 cites W2134704124 @default.
• W2014690503 cites W2146734864 @default.
• W2014690503 cites W2161619010 @default.
• W2014690503 cites W2168861744 @default.
• W2014690503 doi "https://doi.org/10.1067/mva.2002.121755" @default.
• W2014690503 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11932659" @default.
• W2014690503 hasPublicationYear "2002" @default.
• W2014690503 type Work @default.
• W2014690503 sameAs 2014690503 @default.
• W2014690503 citedByCount "30" @default.
• W2014690503 countsByYear W20146905032012 @default.
• W2014690503 countsByYear W20146905032013 @default.
• W2014690503 countsByYear W20146905032014 @default.
• W2014690503 countsByYear W20146905032015 @default.
• W2014690503 countsByYear W20146905032017 @default.
• W2014690503 countsByYear W20146905032018 @default.
• W2014690503 countsByYear W20146905032019 @default.
• W2014690503 countsByYear W20146905032022 @default.
• W2014690503 crossrefType "journal-article" @default.
• W2014690503 hasAuthorship W2014690503A5027703697 @default.
• W2014690503 hasAuthorship W2014690503A5033903155 @default.
• W2014690503 hasAuthorship W2014690503A5037767298 @default.
• W2014690503 hasAuthorship W2014690503A5042777389 @default.
• W2014690503 hasBestOaLocation W20146905031 @default.
• W2014690503 hasConcept C126322002 @default.
• W2014690503 hasConcept C141071460 @default.
• W2014690503 hasConcept C164705383 @default.
• W2014690503 hasConcept C2776098176 @default.
• W2014690503 hasConcept C2776825266 @default.
• W2014690503 hasConcept C2777910003 @default.
• W2014690503 hasConcept C2778261982 @default.
• W2014690503 hasConcept C2778382381 @default.
• W2014690503 hasConcept C2779036427 @default.
• W2014690503 hasConcept C2779519742 @default.
• W2014690503 hasConcept C2779993416 @default.
• W2014690503 hasConcept C2780434524 @default.
• W2014690503 hasConcept C71924100 @default.
• W2014690503 hasConcept C90924648 @default.
• W2014690503 hasConceptScore W2014690503C126322002 @default.
• W2014690503 hasConceptScore W2014690503C141071460 @default.
• W2014690503 hasConceptScore W2014690503C164705383 @default.
• W2014690503 hasConceptScore W2014690503C2776098176 @default.
• W2014690503 hasConceptScore W2014690503C2776825266 @default.
• W2014690503 hasConceptScore W2014690503C2777910003 @default.
• W2014690503 hasConceptScore W2014690503C2778261982 @default.
• W2014690503 hasConceptScore W2014690503C2778382381 @default.
• W2014690503 hasConceptScore W2014690503C2779036427 @default.
• W2014690503 hasConceptScore W2014690503C2779519742 @default.
• W2014690503 hasConceptScore W2014690503C2779993416 @default.
• W2014690503 hasConceptScore W2014690503C2780434524 @default.
• W2014690503 hasConceptScore W2014690503C71924100 @default.
• W2014690503 hasConceptScore W2014690503C90924648 @default.
• W2014690503 hasIssue "4" @default.
• W2014690503 hasLocation W20146905031 @default.
• W2014690503 hasLocation W20146905032 @default.
• W2014690503 hasOpenAccess W2014690503 @default.
• W2014690503 hasPrimaryLocation W20146905031 @default.
• W2014690503 hasRelatedWork W1825026554 @default.
• W2014690503 hasRelatedWork W2035656939 @default.
• W2014690503 hasRelatedWork W2092557691 @default.
• W2014690503 hasRelatedWork W2349929856 @default.
• W2014690503 hasRelatedWork W2350623825 @default.
• W2014690503 hasRelatedWork W2354245752 @default.
• W2014690503 hasRelatedWork W2357380556 @default.
• W2014690503 hasRelatedWork W2362119908 @default.
• W2014690503 hasRelatedWork W2377094410 @default.
• W2014690503 hasRelatedWork W2383779791 @default.
• W2014690503 hasVolume "35" @default.
• W2014690503 isParatext "false" @default.
• W2014690503 isRetracted "false" @default.
• W2014690503 magId "2014690503" @default.
• W2014690503 workType "article" @default.