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- W2014695455 abstract "As a new scaffold for peptidomimetic synthesis, a highly constrained bifunctional diketopiperazine, 4, has been prepared by smooth N-alkylation with tert-butyl bromoacetate. As a first application, we describe herein the synthesis of new peptidomimetics of the Arg-Gly-Asp (RGD) sequence. The product 30, which shows a selective platelet-aggregation inhibiting activity, can be used as a lead for the preparation of more potent products." @default.
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- W2014695455 date "1998-05-01" @default.
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- W2014695455 title "A Constrained Diketopiperazine as a New Scaffold for the Synthesis of Peptidomimetics" @default.
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- W2014695455 doi "https://doi.org/10.1002/(sici)1099-0690(199805)1998:5<853::aid-ejoc853>3.0.co;2-f" @default.
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