FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014700733> ?p ?o ?g. }

• W2014700733 endingPage "62" @default.
• W2014700733 startingPage "53" @default.
• W2014700733 abstract "Autophagy is a cytoplasmic homeostasis pathway, enabling cells to digest their own cytosol, remove toxic protein aggregates, and eliminate defective or surplus organelles. A plenitude of studies has now expanded roles of autophagy to both effector and regulatory functions in innate and adaptive immunity. In its role of an immunological effector, autophagy plays many parts: (i) In its most primeval manifestation, it captures and digests intracellular microbes, (ii) it is an antimicrobial output of Toll-like receptor (TLR) response to pathogen associated molecular patterns (PAMP), and (iii) it is an effector of Th1-Th2 polarization in resistance or susceptibility to intracellular pathogens. As a regulator of immunity, autophagy plays a multitude of functions: (i) It acts as a topological inversion device servicing both innate and adaptive immunity by delivering cytosolic antigens to the lumen of MHC II compartments and cytosolic PAMPs to endosomal TLRs, (ii) it is crucial in T cell repertoire selection in the thymus and control of central tolerance, (iii) it plays a role in T and B cell homeostasis, and (iv) it is of significance for inflammatory pathology. A properly functioning autophagy helps prevent autoimmunity and assists in clearing pathogens. When aberrant, it contributes to human inflammatory disorders such as Crohn's disease." @default.
• W2014700733 created "2016-06-24" @default.
• W2014700733 creator A5091612802 @default.
• W2014700733 date "2009-02-01" @default.
• W2014700733 modified "2023-09-23" @default.
• W2014700733 title "Multiple regulatory and effector roles of autophagy in immunity" @default.
• W2014700733 cites W1559838741 @default.
• W2014700733 cites W1902824041 @default.
• W2014700733 cites W1964414477 @default.
• W2014700733 cites W1967376949 @default.
• W2014700733 cites W1968017409 @default.
• W2014700733 cites W1972336737 @default.
• W2014700733 cites W1972432707 @default.
• W2014700733 cites W1978751572 @default.
• W2014700733 cites W1985969754 @default.
• W2014700733 cites W1986536654 @default.
• W2014700733 cites W1988327539 @default.
• W2014700733 cites W1991300803 @default.
• W2014700733 cites W1994823455 @default.
• W2014700733 cites W2008833365 @default.
• W2014700733 cites W2012451546 @default.
• W2014700733 cites W2015948639 @default.
• W2014700733 cites W2016865932 @default.
• W2014700733 cites W2019951158 @default.
• W2014700733 cites W2020996714 @default.
• W2014700733 cites W2021490026 @default.
• W2014700733 cites W2025824234 @default.
• W2014700733 cites W2026563152 @default.
• W2014700733 cites W2033721990 @default.
• W2014700733 cites W2034132952 @default.
• W2014700733 cites W2036167259 @default.
• W2014700733 cites W2042254284 @default.
• W2014700733 cites W2042260827 @default.
• W2014700733 cites W2045000380 @default.
• W2014700733 cites W2046428284 @default.
• W2014700733 cites W2052104837 @default.
• W2014700733 cites W2064741210 @default.
• W2014700733 cites W2069498930 @default.
• W2014700733 cites W2070216538 @default.
• W2014700733 cites W2072003570 @default.
• W2014700733 cites W2074857405 @default.
• W2014700733 cites W2074917064 @default.
• W2014700733 cites W2078280789 @default.
• W2014700733 cites W2078621117 @default.
• W2014700733 cites W2084708009 @default.
• W2014700733 cites W2085102335 @default.
• W2014700733 cites W2088140877 @default.
• W2014700733 cites W2093083083 @default.
• W2014700733 cites W2096853390 @default.
• W2014700733 cites W2104722369 @default.
• W2014700733 cites W2108205859 @default.
• W2014700733 cites W2109034822 @default.
• W2014700733 cites W2114806766 @default.
• W2014700733 cites W2115742671 @default.
• W2014700733 cites W2116799923 @default.
• W2014700733 cites W2121429373 @default.
• W2014700733 cites W2126764631 @default.
• W2014700733 cites W2134783591 @default.
• W2014700733 cites W2149771125 @default.
• W2014700733 cites W2154663531 @default.
• W2014700733 cites W2154993563 @default.
• W2014700733 cites W2155175976 @default.
• W2014700733 cites W2161340854 @default.
• W2014700733 doi "https://doi.org/10.1016/j.coi.2009.02.002" @default.
• W2014700733 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2788943" @default.
• W2014700733 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19269148" @default.
• W2014700733 hasPublicationYear "2009" @default.
• W2014700733 type Work @default.
• W2014700733 sameAs 2014700733 @default.
• W2014700733 citedByCount "96" @default.
• W2014700733 countsByYear W20147007332012 @default.
• W2014700733 countsByYear W20147007332013 @default.
• W2014700733 countsByYear W20147007332014 @default.
• W2014700733 countsByYear W20147007332015 @default.
• W2014700733 countsByYear W20147007332016 @default.
• W2014700733 countsByYear W20147007332017 @default.
• W2014700733 countsByYear W20147007332018 @default.
• W2014700733 countsByYear W20147007332019 @default.
• W2014700733 countsByYear W20147007332020 @default.
• W2014700733 countsByYear W20147007332021 @default.
• W2014700733 countsByYear W20147007332022 @default.
• W2014700733 countsByYear W20147007332023 @default.
• W2014700733 crossrefType "journal-article" @default.
• W2014700733 hasAuthorship W2014700733A5091612802 @default.
• W2014700733 hasBestOaLocation W20147007332 @default.
• W2014700733 hasConcept C102747710 @default.
• W2014700733 hasConcept C136449434 @default.
• W2014700733 hasConcept C153726182 @default.
• W2014700733 hasConcept C190283241 @default.
• W2014700733 hasConcept C193419808 @default.
• W2014700733 hasConcept C203014093 @default.
• W2014700733 hasConcept C203522944 @default.
• W2014700733 hasConcept C2779341262 @default.
• W2014700733 hasConcept C2780130043 @default.
• W2014700733 hasConcept C51785407 @default.
• W2014700733 hasConcept C54355233 @default.
• W2014700733 hasConcept C79879829 @default.
• W2014700733 hasConcept C86803240 @default.

• next