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- W2014706072 abstract "The early and later effects of estradiol-17β and estriol on the RNA polymerase activities of uterine nuclei obtained from ovariectomized rats were compared. At 4 hr of hormone action both estradiol-17β and estriol stimulated the activity of polymerase I, but not the activities of polymerases II and III. At 24 hr, however, the effect of estriol had disappeared, whereas estradiol-17β stimulated all three polymerase activities. These results indicate that estrogen-induced growth of the uterus occurs in two phases, initiation and maintenance. Estriol initiates uterine growth, but does not maintain the process. Estradiol-17β, in contrast, does both. The differences in the effects of the two estrogens may reside in their different binding affinities." @default.
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- W2014706072 modified "2023-10-17" @default.
- W2014706072 title "Comparative effects of estradiol-17β and estriol on uterine RNA polymerases I, II, and III in vivo" @default.
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- W2014706072 doi "https://doi.org/10.1016/0006-291x(76)90937-2" @default.
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