FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014711772> ?p ?o ?g. }

• W2014711772 endingPage "44" @default.
• W2014711772 startingPage "36" @default.
• W2014711772 abstract "Osteoporosis and its complications represent one of the most important causes of morbidity and mortality around the world. Moreover, its management presents an important economic problem. Although osteoporosis is a worldwide health problem, there are many differences in ethnic groups regarding disease morbidity and drug treatment efficacy. This review analyzed clinical response data of two major osteoporotic treatments (vitamin D and estrogens) regarding four major human races (Asian, Caucasian, Hispanic and Negroid). From clinical studies, Asians seem to be more vitamin-D-sensitive while Caucasians appear more estrogen-sensitive than other human races. Different drug responses may be related to allelic variants in their signaling genes such as those for the vitamin D receptor (VDR) and estrogen receptor-alpha (ER alpha). Some polymorphisms of VDR and ER alpha loci appear to be genetic determinants of osteoporotic risk: ApaI-BsmI-TaqI, FokI variants and poly(A) repeats in VDR; PvuII-XbaI variants and (TA) repeats in ER alpha. Also, because of specific ethnic allele distributions, these VDR and ER alpha polymorphisms may be involved in race differences of osteoporosis treatment responses. Future studies and preventive strategies for the management of osteoporosis need to take into account these racial and genetic factors." @default.
• W2014711772 created "2016-06-24" @default.
• W2014711772 creator A5061121783 @default.
• W2014711772 date "2005-01-01" @default.
• W2014711772 modified "2023-10-02" @default.
• W2014711772 title "Human races and pharmacogenomics of effective bone treatments" @default.
• W2014711772 cites W1526381611 @default.
• W2014711772 cites W1979037737 @default.
• W2014711772 cites W1979201224 @default.
• W2014711772 cites W1989554921 @default.
• W2014711772 cites W1989693389 @default.
• W2014711772 cites W2004509621 @default.
• W2014711772 cites W2008550424 @default.
• W2014711772 cites W2009180025 @default.
• W2014711772 cites W2013729184 @default.
• W2014711772 cites W2014403326 @default.
• W2014711772 cites W2018554518 @default.
• W2014711772 cites W2019521296 @default.
• W2014711772 cites W2021381092 @default.
• W2014711772 cites W2025979615 @default.
• W2014711772 cites W2027765842 @default.
• W2014711772 cites W2035958841 @default.
• W2014711772 cites W2037994233 @default.
• W2014711772 cites W2043382556 @default.
• W2014711772 cites W2046444478 @default.
• W2014711772 cites W2047730950 @default.
• W2014711772 cites W2048941578 @default.
• W2014711772 cites W2049133402 @default.
• W2014711772 cites W2050834533 @default.
• W2014711772 cites W2072270943 @default.
• W2014711772 cites W2078140516 @default.
• W2014711772 cites W2080535189 @default.
• W2014711772 cites W2081928163 @default.
• W2014711772 cites W2083530199 @default.
• W2014711772 cites W2091803762 @default.
• W2014711772 cites W2118345884 @default.
• W2014711772 cites W2118728107 @default.
• W2014711772 cites W2121398847 @default.
• W2014711772 cites W2133112709 @default.
• W2014711772 cites W2154987378 @default.
• W2014711772 cites W2161103103 @default.
• W2014711772 cites W2163893730 @default.
• W2014711772 cites W2164374136 @default.
• W2014711772 cites W2168328801 @default.
• W2014711772 cites W2169624708 @default.
• W2014711772 doi "https://doi.org/10.1080/09513590400019437" @default.
• W2014711772 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15969245" @default.
• W2014711772 hasPublicationYear "2005" @default.
• W2014711772 type Work @default.
• W2014711772 sameAs 2014711772 @default.
• W2014711772 citedByCount "24" @default.
• W2014711772 countsByYear W20147117722012 @default.
• W2014711772 countsByYear W20147117722013 @default.
• W2014711772 countsByYear W20147117722014 @default.
• W2014711772 countsByYear W20147117722015 @default.
• W2014711772 countsByYear W20147117722017 @default.
• W2014711772 countsByYear W20147117722018 @default.
• W2014711772 countsByYear W20147117722023 @default.
• W2014711772 crossrefType "journal-article" @default.
• W2014711772 hasAuthorship W2014711772A5061121783 @default.
• W2014711772 hasConcept C104317684 @default.
• W2014711772 hasConcept C121608353 @default.
• W2014711772 hasConcept C124490489 @default.
• W2014711772 hasConcept C126322002 @default.
• W2014711772 hasConcept C134018914 @default.
• W2014711772 hasConcept C135763542 @default.
• W2014711772 hasConcept C149737253 @default.
• W2014711772 hasConcept C170734499 @default.
• W2014711772 hasConcept C172313692 @default.
• W2014711772 hasConcept C179639408 @default.
• W2014711772 hasConcept C180754005 @default.
• W2014711772 hasConcept C2776541429 @default.
• W2014711772 hasConcept C2779105492 @default.
• W2014711772 hasConcept C2779134260 @default.
• W2014711772 hasConcept C2781308329 @default.
• W2014711772 hasConcept C530470458 @default.
• W2014711772 hasConcept C54355233 @default.
• W2014711772 hasConcept C55775858 @default.
• W2014711772 hasConcept C60644358 @default.
• W2014711772 hasConcept C71924100 @default.
• W2014711772 hasConcept C84606932 @default.
• W2014711772 hasConcept C86803240 @default.
• W2014711772 hasConcept C98274493 @default.
• W2014711772 hasConceptScore W2014711772C104317684 @default.
• W2014711772 hasConceptScore W2014711772C121608353 @default.
• W2014711772 hasConceptScore W2014711772C124490489 @default.
• W2014711772 hasConceptScore W2014711772C126322002 @default.
• W2014711772 hasConceptScore W2014711772C134018914 @default.
• W2014711772 hasConceptScore W2014711772C135763542 @default.
• W2014711772 hasConceptScore W2014711772C149737253 @default.
• W2014711772 hasConceptScore W2014711772C170734499 @default.
• W2014711772 hasConceptScore W2014711772C172313692 @default.
• W2014711772 hasConceptScore W2014711772C179639408 @default.
• W2014711772 hasConceptScore W2014711772C180754005 @default.
• W2014711772 hasConceptScore W2014711772C2776541429 @default.
• W2014711772 hasConceptScore W2014711772C2779105492 @default.
• W2014711772 hasConceptScore W2014711772C2779134260 @default.
• W2014711772 hasConceptScore W2014711772C2781308329 @default.

• next