Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014714141> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W2014714141 endingPage "1267" @default.
- W2014714141 startingPage "1256" @default.
- W2014714141 abstract "OBJECTIVE: We examined the therapeutic benefits of intra-arterially administered papaverine for treatment of symptomatic cerebral vasospasm after subarachnoid hemorrhage (SAH). Recent advances in microcatheter technology have facilitated endovascular approaches to vessels experiencing vasospasm after SAH. However, despite numerous encouraging anecdotal reports, no rigorous examination of the efficacy of these procedures has been published. Intra-arterial infusion of papaverine has become part of the standard management of vasospasm at some centers. METHODS: We examined a series of 31 patients undergoing papaverine infusion for the treatment of symptomatic vasospasm after SAH. The patients were a subgroup of the series enrolled in the North American Trial of Tirilizad for Aneurysmal Subarachnoid Hemorrhage. These individuals were matched with patients from the same trial who exhibited similar clinical characteristics (including the degree of vasospasm and the modified Glasgow Coma Scale scores measured at the time of admission and on the day of papaverine infusion) but received medical management alone for vasospasm. RESULTS: Logistic regression analysis comparing these two groups showed no statistical difference in the 3-month Glasgow Outcome Scale scores between patients receiving papaverine and control subjects (58% favorable outcomes for control subjects versus 45% for patients receiving papaverine). CONCLUSION: Although isolated series documenting clinical successes have prompted the increased use of papaverine as a treatment for vasospasm after SAH, this series suggests that, as it is currently being used, the drug does not provide added benefits, compared with medical treatment of vasospasm alone. This result does not preclude the possibility that alterations in the timing of or indications for drug treatment might produce beneficial effects." @default.
- W2014714141 created "2016-06-24" @default.
- W2014714141 creator A5045058057 @default.
- W2014714141 creator A5052124322 @default.
- W2014714141 creator A5056267685 @default.
- W2014714141 creator A5063205184 @default.
- W2014714141 creator A5078044974 @default.
- W2014714141 date "1998-06-01" @default.
- W2014714141 modified "2023-10-12" @default.
- W2014714141 title "Intra-arterially Administered Papaverine for the Treatment of Symptomatic Cerebral Vasospasm" @default.
- W2014714141 cites W124099076 @default.
- W2014714141 cites W143780562 @default.
- W2014714141 cites W1573946313 @default.
- W2014714141 cites W1971933032 @default.
- W2014714141 cites W1971962670 @default.
- W2014714141 cites W1972755530 @default.
- W2014714141 cites W1998851907 @default.
- W2014714141 cites W2013439044 @default.
- W2014714141 cites W2085224951 @default.
- W2014714141 cites W2091882928 @default.
- W2014714141 cites W2120309516 @default.
- W2014714141 cites W2165516379 @default.
- W2014714141 cites W2170937426 @default.
- W2014714141 cites W2325628738 @default.
- W2014714141 cites W2333793410 @default.
- W2014714141 cites W2334222771 @default.
- W2014714141 cites W2409631027 @default.
- W2014714141 cites W2420438576 @default.
- W2014714141 cites W4235583413 @default.
- W2014714141 cites W4297583176 @default.
- W2014714141 cites W4376595952 @default.
- W2014714141 doi "https://doi.org/10.1097/00006123-199806000-00031" @default.
- W2014714141 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9632183" @default.
- W2014714141 hasPublicationYear "1998" @default.
- W2014714141 type Work @default.
- W2014714141 sameAs 2014714141 @default.
- W2014714141 citedByCount "127" @default.
- W2014714141 countsByYear W20147141412012 @default.
- W2014714141 countsByYear W20147141412013 @default.
- W2014714141 countsByYear W20147141412014 @default.
- W2014714141 countsByYear W20147141412015 @default.
- W2014714141 countsByYear W20147141412017 @default.
- W2014714141 countsByYear W20147141412018 @default.
- W2014714141 countsByYear W20147141412020 @default.
- W2014714141 countsByYear W20147141412022 @default.
- W2014714141 countsByYear W20147141412023 @default.
- W2014714141 crossrefType "journal-article" @default.
- W2014714141 hasAuthorship W2014714141A5045058057 @default.
- W2014714141 hasAuthorship W2014714141A5052124322 @default.
- W2014714141 hasAuthorship W2014714141A5056267685 @default.
- W2014714141 hasAuthorship W2014714141A5063205184 @default.
- W2014714141 hasAuthorship W2014714141A5078044974 @default.
- W2014714141 hasConcept C17624336 @default.
- W2014714141 hasConcept C2776820941 @default.
- W2014714141 hasConcept C2776952824 @default.
- W2014714141 hasConcept C2777736543 @default.
- W2014714141 hasConcept C2777796830 @default.
- W2014714141 hasConcept C2778506911 @default.
- W2014714141 hasConcept C42219234 @default.
- W2014714141 hasConcept C71924100 @default.
- W2014714141 hasConceptScore W2014714141C17624336 @default.
- W2014714141 hasConceptScore W2014714141C2776820941 @default.
- W2014714141 hasConceptScore W2014714141C2776952824 @default.
- W2014714141 hasConceptScore W2014714141C2777736543 @default.
- W2014714141 hasConceptScore W2014714141C2777796830 @default.
- W2014714141 hasConceptScore W2014714141C2778506911 @default.
- W2014714141 hasConceptScore W2014714141C42219234 @default.
- W2014714141 hasConceptScore W2014714141C71924100 @default.
- W2014714141 hasIssue "6" @default.
- W2014714141 hasLocation W20147141411 @default.
- W2014714141 hasLocation W20147141412 @default.
- W2014714141 hasOpenAccess W2014714141 @default.
- W2014714141 hasPrimaryLocation W20147141411 @default.
- W2014714141 hasRelatedWork W1974041169 @default.
- W2014714141 hasRelatedWork W1982932633 @default.
- W2014714141 hasRelatedWork W2009268034 @default.
- W2014714141 hasRelatedWork W2014714141 @default.
- W2014714141 hasRelatedWork W2028373316 @default.
- W2014714141 hasRelatedWork W2052810380 @default.
- W2014714141 hasRelatedWork W2091882928 @default.
- W2014714141 hasRelatedWork W2324907069 @default.
- W2014714141 hasRelatedWork W2414991892 @default.
- W2014714141 hasRelatedWork W2617692001 @default.
- W2014714141 hasVolume "42" @default.
- W2014714141 isParatext "false" @default.
- W2014714141 isRetracted "false" @default.
- W2014714141 magId "2014714141" @default.
- W2014714141 workType "article" @default.