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- W2014730435 abstract "In stringent bacteria, amino acid starvation is known to arrest gross RNA synthesis. There is accumulating evidence suggesting that this amino acid control of RNA synthesis is not coordinate: rel gene regulates rRNA and tRNA but not mRNA synthesis [ 11. It was shown for the tryptophan, histidine and arginine systems that during starvation for the respective amino acid the corresponding mRNA is synthesized preferentially [2-61. Moreover, the possibility of inducing lac mRNA synthesis during amino acid starvation suggests that mRNA synthesis is not restricted to the operon controlling the synthesis of the amino acid which is withdrawn [9121 . There..are two ways for the determination of mRNA synthesized during amino acid starvation. The first utilizes the hybridization technique and employs appropriate genetic tools [2-4, 7-81 . The second assesses mRNA by its capacity to direct enzyme synthesis [6, 91. Using the second method we have found that in a histidine constitutive mutant histidine mRNA is accumulated during starvation for leucine or threonine." @default.
- W2014730435 created "2016-06-24" @default.
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- W2014730435 date "1971-09-15" @default.
- W2014730435 modified "2023-09-27" @default.
- W2014730435 title "Effect of amino acid starvation on constitutive synthesis of histidine mRNA" @default.
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- W2014730435 doi "https://doi.org/10.1016/0014-5793(71)80568-9" @default.
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