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- W2014731077 abstract "A sensitive and accurate liquid chromatography method with mass spectrometry detection was developed and validated for the quantification of dabigatran (Pradaxa®) and rivaroxaban (Xarelto®). 13C6-dabigatran and 13C6-rivaroxaban were used as the internal standard. A single-step protein precipitation was used for plasma sample preparation. This method was validated with respect to linearity, selectivity, inter- and intra-day precision and accuracy, limit of quantification and stability. The lower limit of quantification was 2.5 ng/mL for both drugs in plasma." @default.
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- W2014731077 date "2014-11-01" @default.
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- W2014731077 title "Simultaneous determination of rivaroxaban and dabigatran levels in human plasma by high-performance liquid chromatography–tandem mass spectrometry" @default.
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- W2014731077 doi "https://doi.org/10.1016/j.jpba.2014.08.011" @default.
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