Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014733169> ?p ?o ?g. }
- W2014733169 endingPage "1447" @default.
- W2014733169 startingPage "1440" @default.
- W2014733169 abstract "Prenatal ethanol exposure and stress have each been shown to have significant effects on the immune system. This study examined the possible interactive effects of prenatal ethanol exposure and exposure to stress later in life on the immune system. Differential vulnerability to these challenges in female and male offspring was assessed. At 5 to 6 months of age, female and male offspring from prenatal ethanol-exposed (E), pair-fed (PF), and ad libitum-fed control (C) conditions were exposed to 0, 1, or 3 days of cold (4°C). At the end of the cold period, the proliferative response of splenic lymphocytes to the mitogens concanavalin A (Con A) and pokeweed mitogen (PWM) was assessed. The data demonstrate a significant interactive effect between prenatal ethanol exposure and cold stress in female offspring. After 1 day of cold stress, E females had significantly increased PWM-induced lymphocyte proliferation compared with PF and C females, and significantly increased Con A-induced lymphocyte proliferation compared with PF females. There were no differences in PWM or Con A-induced lymphocyte proliferation among E, PF, and C females after 0 or 3 days of cold stress, nor among E, PF, and C males on any test day. Regardless of prenatal treatment, females exposed to 1 or 3 days of cold had significantly greater basal plasma corticosterone levels than females not exposed to cold. In contrast, only E males exposed to 1 or 3 days of cold had significantly increased basal plasma corticosterone levels, compared with E males not exposed to cold; PF and C males showed no significant change in basal corticosterone after cold stress. These data demonstrate that, in response to the challenge of cold stress, changes in lymphocyte proliferation to PWM and Con A may occur selectively in E females. Moreover, the interactive effects of prenatal ethanol and cold stress may result in enhanced rather than suppressed immune responsiveness." @default.
- W2014733169 created "2016-06-24" @default.
- W2014733169 creator A5025545914 @default.
- W2014733169 creator A5032808224 @default.
- W2014733169 creator A5037987356 @default.
- W2014733169 creator A5055803078 @default.
- W2014733169 creator A5067935354 @default.
- W2014733169 creator A5090884938 @default.
- W2014733169 date "1997-11-01" @default.
- W2014733169 modified "2023-09-27" @default.
- W2014733169 title "The Effect of Cold Stress on Lymphocyte Proliferation in Fetal Ethanol-Exposed Rats" @default.
- W2014733169 cites W116230673 @default.
- W2014733169 cites W1485094869 @default.
- W2014733169 cites W1643642339 @default.
- W2014733169 cites W1648974646 @default.
- W2014733169 cites W1842467494 @default.
- W2014733169 cites W1965978320 @default.
- W2014733169 cites W1973365761 @default.
- W2014733169 cites W1977448828 @default.
- W2014733169 cites W1977589149 @default.
- W2014733169 cites W1981515634 @default.
- W2014733169 cites W1982086632 @default.
- W2014733169 cites W1982765975 @default.
- W2014733169 cites W1991393778 @default.
- W2014733169 cites W1993354537 @default.
- W2014733169 cites W1993445602 @default.
- W2014733169 cites W1998043384 @default.
- W2014733169 cites W1998285682 @default.
- W2014733169 cites W2001101925 @default.
- W2014733169 cites W2001214757 @default.
- W2014733169 cites W2001687421 @default.
- W2014733169 cites W2003681769 @default.
- W2014733169 cites W2003895990 @default.
- W2014733169 cites W2004767882 @default.
- W2014733169 cites W2007289040 @default.
- W2014733169 cites W2009738677 @default.
- W2014733169 cites W2014523798 @default.
- W2014733169 cites W2016019351 @default.
- W2014733169 cites W2019357278 @default.
- W2014733169 cites W2020126192 @default.
- W2014733169 cites W2024207873 @default.
- W2014733169 cites W2026216918 @default.
- W2014733169 cites W2029883755 @default.
- W2014733169 cites W2031934304 @default.
- W2014733169 cites W2032802258 @default.
- W2014733169 cites W2039412948 @default.
- W2014733169 cites W2040074509 @default.
- W2014733169 cites W2042207199 @default.
- W2014733169 cites W2045988701 @default.
- W2014733169 cites W2051431390 @default.
- W2014733169 cites W2056210064 @default.
- W2014733169 cites W2059658263 @default.
- W2014733169 cites W2061897214 @default.
- W2014733169 cites W2062055332 @default.
- W2014733169 cites W2062825661 @default.
- W2014733169 cites W2066593395 @default.
- W2014733169 cites W2067334677 @default.
- W2014733169 cites W2069970665 @default.
- W2014733169 cites W2071173631 @default.
- W2014733169 cites W2075695346 @default.
- W2014733169 cites W2077846264 @default.
- W2014733169 cites W2087628445 @default.
- W2014733169 cites W2091096455 @default.
- W2014733169 cites W2133258632 @default.
- W2014733169 cites W2135372888 @default.
- W2014733169 cites W2168215604 @default.
- W2014733169 cites W2410628480 @default.
- W2014733169 cites W2411564279 @default.
- W2014733169 cites W4238174545 @default.
- W2014733169 cites W4295785503 @default.
- W2014733169 doi "https://doi.org/10.1111/j.1530-0277.1997.tb04474.x" @default.
- W2014733169 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9394116" @default.
- W2014733169 hasPublicationYear "1997" @default.
- W2014733169 type Work @default.
- W2014733169 sameAs 2014733169 @default.
- W2014733169 citedByCount "21" @default.
- W2014733169 countsByYear W20147331692012 @default.
- W2014733169 countsByYear W20147331692013 @default.
- W2014733169 countsByYear W20147331692015 @default.
- W2014733169 countsByYear W20147331692019 @default.
- W2014733169 crossrefType "journal-article" @default.
- W2014733169 hasAuthorship W2014733169A5025545914 @default.
- W2014733169 hasAuthorship W2014733169A5032808224 @default.
- W2014733169 hasAuthorship W2014733169A5037987356 @default.
- W2014733169 hasAuthorship W2014733169A5055803078 @default.
- W2014733169 hasAuthorship W2014733169A5067935354 @default.
- W2014733169 hasAuthorship W2014733169A5090884938 @default.
- W2014733169 hasConcept C112672928 @default.
- W2014733169 hasConcept C126322002 @default.
- W2014733169 hasConcept C134018914 @default.
- W2014733169 hasConcept C16685009 @default.
- W2014733169 hasConcept C172680121 @default.
- W2014733169 hasConcept C19869320 @default.
- W2014733169 hasConcept C202751555 @default.
- W2014733169 hasConcept C203014093 @default.
- W2014733169 hasConcept C2776443723 @default.
- W2014733169 hasConcept C2777761686 @default.
- W2014733169 hasConcept C2778024521 @default.