Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014753456> ?p ?o ?g. }
- W2014753456 endingPage "251" @default.
- W2014753456 startingPage "246" @default.
- W2014753456 abstract "Non-specific adsorption of proteins at solid/liquid interfaces is a major problem in the use of synthetic biomaterials and in ultrasensitive detection methods. Grafting surfaces with a dense layer of poly(ethylene glycol) (PEG) or other polymers is a most widely used strategy to solve this task. While such modified surfaces have been characterized by their ability to resist protein adsorption, the polymer layers themselves have rarely been studied in fine detail. Atomic force microscopy (AFM) using the pulsed force mode (PFM), is an ideal technique to investigate structural features and physiochemical properties of surfaces because topology and adhesion are simultaneously detected with high lateral resolution. In the present study, PFM-AFM was applied to thoroughly characterize different stages of glass derivatization, up to the formation of a dense PEG layer. Lateral inhomogeneities in topology and/or adhesion were observed at all stages before PEG attachment. The covalently bound PEG, however, was seen to form a densely packed monolayer with maximal thickness, smooth surface, and weak adhesion. Thus, PFM-AFM appears to be a valuable tool for the characterization of protein-repelling surfaces in solution." @default.
- W2014753456 created "2016-06-24" @default.
- W2014753456 creator A5011373471 @default.
- W2014753456 creator A5017470395 @default.
- W2014753456 creator A5037494404 @default.
- W2014753456 creator A5039912212 @default.
- W2014753456 creator A5077002898 @default.
- W2014753456 date "2004-11-01" @default.
- W2014753456 modified "2023-10-16" @default.
- W2014753456 title "Monitoring of glass derivatization with pulsed force mode atomic force microscopy" @default.
- W2014753456 cites W1974262428 @default.
- W2014753456 cites W1979851126 @default.
- W2014753456 cites W1980416838 @default.
- W2014753456 cites W1986257246 @default.
- W2014753456 cites W1991013335 @default.
- W2014753456 cites W1991240946 @default.
- W2014753456 cites W1991661839 @default.
- W2014753456 cites W1996045920 @default.
- W2014753456 cites W1996520089 @default.
- W2014753456 cites W2010227280 @default.
- W2014753456 cites W2010711853 @default.
- W2014753456 cites W2011351597 @default.
- W2014753456 cites W2016678539 @default.
- W2014753456 cites W2017150085 @default.
- W2014753456 cites W2021517658 @default.
- W2014753456 cites W2024004515 @default.
- W2014753456 cites W2032095873 @default.
- W2014753456 cites W2034076315 @default.
- W2014753456 cites W2037250162 @default.
- W2014753456 cites W2039112917 @default.
- W2014753456 cites W2039773413 @default.
- W2014753456 cites W2042541446 @default.
- W2014753456 cites W2050138771 @default.
- W2014753456 cites W2053080609 @default.
- W2014753456 cites W2059639914 @default.
- W2014753456 cites W2061356326 @default.
- W2014753456 cites W2072465612 @default.
- W2014753456 cites W2075676774 @default.
- W2014753456 cites W2078528221 @default.
- W2014753456 cites W2079048123 @default.
- W2014753456 cites W2082886859 @default.
- W2014753456 cites W2087979840 @default.
- W2014753456 cites W2090106568 @default.
- W2014753456 cites W2090284578 @default.
- W2014753456 cites W2118317128 @default.
- W2014753456 cites W2123697633 @default.
- W2014753456 cites W2147520793 @default.
- W2014753456 cites W2160471784 @default.
- W2014753456 cites W2165572045 @default.
- W2014753456 cites W2461824501 @default.
- W2014753456 doi "https://doi.org/10.1002/jemt.20124" @default.
- W2014753456 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15630686" @default.
- W2014753456 hasPublicationYear "2004" @default.
- W2014753456 type Work @default.
- W2014753456 sameAs 2014753456 @default.
- W2014753456 citedByCount "4" @default.
- W2014753456 crossrefType "journal-article" @default.
- W2014753456 hasAuthorship W2014753456A5011373471 @default.
- W2014753456 hasAuthorship W2014753456A5017470395 @default.
- W2014753456 hasAuthorship W2014753456A5037494404 @default.
- W2014753456 hasAuthorship W2014753456A5039912212 @default.
- W2014753456 hasAuthorship W2014753456A5077002898 @default.
- W2014753456 hasBestOaLocation W20147534561 @default.
- W2014753456 hasConcept C10138342 @default.
- W2014753456 hasConcept C102951782 @default.
- W2014753456 hasConcept C120665830 @default.
- W2014753456 hasConcept C121332964 @default.
- W2014753456 hasConcept C127413603 @default.
- W2014753456 hasConcept C138268822 @default.
- W2014753456 hasConcept C147080431 @default.
- W2014753456 hasConcept C150394285 @default.
- W2014753456 hasConcept C154945302 @default.
- W2014753456 hasConcept C159985019 @default.
- W2014753456 hasConcept C162324750 @default.
- W2014753456 hasConcept C162356407 @default.
- W2014753456 hasConcept C171250308 @default.
- W2014753456 hasConcept C178790620 @default.
- W2014753456 hasConcept C185592680 @default.
- W2014753456 hasConcept C192562407 @default.
- W2014753456 hasConcept C2776923573 @default.
- W2014753456 hasConcept C2777516009 @default.
- W2014753456 hasConcept C2779227376 @default.
- W2014753456 hasConcept C41008148 @default.
- W2014753456 hasConcept C42360764 @default.
- W2014753456 hasConcept C43617362 @default.
- W2014753456 hasConcept C521977710 @default.
- W2014753456 hasConcept C54400483 @default.
- W2014753456 hasConcept C7070889 @default.
- W2014753456 hasConcept C84416704 @default.
- W2014753456 hasConcept C88001094 @default.
- W2014753456 hasConceptScore W2014753456C10138342 @default.
- W2014753456 hasConceptScore W2014753456C102951782 @default.
- W2014753456 hasConceptScore W2014753456C120665830 @default.
- W2014753456 hasConceptScore W2014753456C121332964 @default.
- W2014753456 hasConceptScore W2014753456C127413603 @default.
- W2014753456 hasConceptScore W2014753456C138268822 @default.
- W2014753456 hasConceptScore W2014753456C147080431 @default.
- W2014753456 hasConceptScore W2014753456C150394285 @default.