FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014763774> ?p ?o ?g. }

• W2014763774 endingPage "312" @default.
• W2014763774 startingPage "309" @default.
• W2014763774 abstract "A considerable body of evidence now shows that PrP (prion protein) binds metal ions with high affinity and it has been claimed that the binding of copper (II) ions to PrP confers SOD (superoxide dismutase) activity. In turn, it has been suggested that PrP is a synaptic dismutase and that loss of this function, as a result of the conversion of PrPC into PrPSc, results in pathology and hence morbidity associated with prion disease. However, contrary to previous reports, in the present study we have found that PrP exhibits no detectable dismutase activity above baseline levels measured for copper (II) ions in water when assayed using a reliable procedure with a detection limit of at least 2 units of activity/mg of protein. This was true when the assay was performed with either PrP refolded from a denatured state in the presence of copper, as in previous studies, or native PrP loaded with copper. Thus if PrP has any role in oxidative stress, it must be indirect as a regulator of protective cellular responses." @default.
• W2014763774 created "2016-06-24" @default.
• W2014763774 creator A5001816110 @default.
• W2014763774 creator A5028812792 @default.
• W2014763774 creator A5030464239 @default.
• W2014763774 creator A5050202818 @default.
• W2014763774 creator A5058571656 @default.
• W2014763774 creator A5058804697 @default.
• W2014763774 date "2005-11-22" @default.
• W2014763774 modified "2023-09-27" @default.
• W2014763774 title "Recombinant prion protein does not possess SOD-1 activity" @default.
• W2014763774 cites W1502562397 @default.
• W2014763774 cites W1557724928 @default.
• W2014763774 cites W1704732331 @default.
• W2014763774 cites W1829344915 @default.
• W2014763774 cites W1972409470 @default.
• W2014763774 cites W1974443289 @default.
• W2014763774 cites W1993986579 @default.
• W2014763774 cites W2010745676 @default.
• W2014763774 cites W2012128918 @default.
• W2014763774 cites W2013679718 @default.
• W2014763774 cites W2017634178 @default.
• W2014763774 cites W2020146455 @default.
• W2014763774 cites W2022118976 @default.
• W2014763774 cites W2022735447 @default.
• W2014763774 cites W2022993326 @default.
• W2014763774 cites W2024256697 @default.
• W2014763774 cites W2027686813 @default.
• W2014763774 cites W2036645353 @default.
• W2014763774 cites W2053636966 @default.
• W2014763774 cites W2053898989 @default.
• W2014763774 cites W2064722614 @default.
• W2014763774 cites W2065310894 @default.
• W2014763774 cites W2071046730 @default.
• W2014763774 cites W2080671690 @default.
• W2014763774 cites W2090184114 @default.
• W2014763774 cites W2095490690 @default.
• W2014763774 cites W2109401365 @default.
• W2014763774 cites W2138038687 @default.
• W2014763774 cites W2143795630 @default.
• W2014763774 cites W2147276565 @default.
• W2014763774 cites W2172245413 @default.
• W2014763774 cites W2324660492 @default.
• W2014763774 doi "https://doi.org/10.1042/bj20051236" @default.
• W2014763774 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1316266" @default.
• W2014763774 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16156720" @default.
• W2014763774 hasPublicationYear "2005" @default.
• W2014763774 type Work @default.
• W2014763774 sameAs 2014763774 @default.
• W2014763774 citedByCount "76" @default.
• W2014763774 countsByYear W20147637742012 @default.
• W2014763774 countsByYear W20147637742013 @default.
• W2014763774 countsByYear W20147637742014 @default.
• W2014763774 countsByYear W20147637742015 @default.
• W2014763774 countsByYear W20147637742016 @default.
• W2014763774 countsByYear W20147637742017 @default.
• W2014763774 countsByYear W20147637742018 @default.
• W2014763774 countsByYear W20147637742019 @default.
• W2014763774 countsByYear W20147637742020 @default.
• W2014763774 crossrefType "journal-article" @default.
• W2014763774 hasAuthorship W2014763774A5001816110 @default.
• W2014763774 hasAuthorship W2014763774A5028812792 @default.
• W2014763774 hasAuthorship W2014763774A5030464239 @default.
• W2014763774 hasAuthorship W2014763774A5050202818 @default.
• W2014763774 hasAuthorship W2014763774A5058571656 @default.
• W2014763774 hasAuthorship W2014763774A5058804697 @default.
• W2014763774 hasBestOaLocation W20147637742 @default.
• W2014763774 hasConcept C104317684 @default.
• W2014763774 hasConcept C126322002 @default.
• W2014763774 hasConcept C153911025 @default.
• W2014763774 hasConcept C178790620 @default.
• W2014763774 hasConcept C185592680 @default.
• W2014763774 hasConcept C2775838275 @default.
• W2014763774 hasConcept C2776151105 @default.
• W2014763774 hasConcept C2778248901 @default.
• W2014763774 hasConcept C2779134260 @default.
• W2014763774 hasConcept C3019804061 @default.
• W2014763774 hasConcept C40767141 @default.
• W2014763774 hasConcept C544778455 @default.
• W2014763774 hasConcept C55493867 @default.
• W2014763774 hasConcept C6929976 @default.
• W2014763774 hasConcept C71924100 @default.
• W2014763774 hasConcept C86803240 @default.
• W2014763774 hasConceptScore W2014763774C104317684 @default.
• W2014763774 hasConceptScore W2014763774C126322002 @default.
• W2014763774 hasConceptScore W2014763774C153911025 @default.
• W2014763774 hasConceptScore W2014763774C178790620 @default.
• W2014763774 hasConceptScore W2014763774C185592680 @default.
• W2014763774 hasConceptScore W2014763774C2775838275 @default.
• W2014763774 hasConceptScore W2014763774C2776151105 @default.
• W2014763774 hasConceptScore W2014763774C2778248901 @default.
• W2014763774 hasConceptScore W2014763774C2779134260 @default.
• W2014763774 hasConceptScore W2014763774C3019804061 @default.
• W2014763774 hasConceptScore W2014763774C40767141 @default.
• W2014763774 hasConceptScore W2014763774C544778455 @default.
• W2014763774 hasConceptScore W2014763774C55493867 @default.
• W2014763774 hasConceptScore W2014763774C6929976 @default.
• W2014763774 hasConceptScore W2014763774C71924100 @default.

• next