FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014764712> ?p ?o ?g. }

• W2014764712 endingPage "1573" @default.
• W2014764712 startingPage "1562" @default.
• W2014764712 abstract "In this study we investigated the use of a fibrin hydrogel to improve the potential of a polyurethane (PU) scaffold-based system for articular cartilage tissue engineering. PU-only (no-fibrin) and PU-fibrin (fibrin) composites were cultured for up to 28 days and analyzed for DNA content, glycosaminoglycan (GAG) content, type II collagen content, GAG release, and gene expression of aggrecan, collagen I, and collagen II. The use of fibrin allowed for higher viable cell-seeding efficiency (10% higher DNA content on day 2 in fibrin versus no-fibrin composites) and more even cell distribution on seeding, a more than 3-fold increase in the percentage of newly synthesized GAG retained in the constructs, and 2- to 6-fold higher levels of type II collagen and aggrecan gene expression through day 14. Addition of aprotinin to the medium inhibited fibrin degradation, most noticeably in the center of the constructs, but had little effect on biochemical composition or gene expression. Short-term mechanical compression (0-10% sinusoidal strain at 0.1 Hz for 1 h, applied twice daily for 3 days) doubled the rate of GAG release from the constructs, but had little effect on gene expression, regardless of the presence of fibrin. Although further work is needed to optimize this system, the addition of fibrin hydrogel to encapsulate cells in the stiff, macroporous PU scaffold is a step forward in our approach to articular cartilage tissue engineering." @default.
• W2014764712 created "2016-06-24" @default.
• W2014764712 creator A5001667773 @default.
• W2014764712 creator A5016932546 @default.
• W2014764712 creator A5055387674 @default.
• W2014764712 creator A5056006133 @default.
• W2014764712 creator A5058887915 @default.
• W2014764712 creator A5059887246 @default.
• W2014764712 date "2005-09-01" @default.
• W2014764712 modified "2023-10-18" @default.
• W2014764712 title "Fibrin–Polyurethane Composites for Articular Cartilage Tissue Engineering: A Preliminary Analysis" @default.
• W2014764712 cites W100567210 @default.
• W2014764712 cites W1977779461 @default.
• W2014764712 cites W1984279075 @default.
• W2014764712 cites W1985670094 @default.
• W2014764712 cites W1996295528 @default.
• W2014764712 cites W1997299213 @default.
• W2014764712 cites W1997403931 @default.
• W2014764712 cites W2002128589 @default.
• W2014764712 cites W2003867975 @default.
• W2014764712 cites W2004058379 @default.
• W2014764712 cites W2008717401 @default.
• W2014764712 cites W2009350275 @default.
• W2014764712 cites W2012388796 @default.
• W2014764712 cites W2013924211 @default.
• W2014764712 cites W2025395652 @default.
• W2014764712 cites W2026420278 @default.
• W2014764712 cites W2027358169 @default.
• W2014764712 cites W2031904484 @default.
• W2014764712 cites W2032255522 @default.
• W2014764712 cites W2050273631 @default.
• W2014764712 cites W2053251151 @default.
• W2014764712 cites W2062530748 @default.
• W2014764712 cites W2069925193 @default.
• W2014764712 cites W2084976018 @default.
• W2014764712 cites W2087644457 @default.
• W2014764712 cites W2089510926 @default.
• W2014764712 cites W2093066616 @default.
• W2014764712 cites W2129125900 @default.
• W2014764712 cites W2131456542 @default.
• W2014764712 cites W2147526125 @default.
• W2014764712 cites W2164480016 @default.
• W2014764712 cites W4252935386 @default.
• W2014764712 doi "https://doi.org/10.1089/ten.2005.11.1562" @default.
• W2014764712 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16259610" @default.
• W2014764712 hasPublicationYear "2005" @default.
• W2014764712 type Work @default.
• W2014764712 sameAs 2014764712 @default.
• W2014764712 citedByCount "140" @default.
• W2014764712 countsByYear W20147647122012 @default.
• W2014764712 countsByYear W20147647122013 @default.
• W2014764712 countsByYear W20147647122014 @default.
• W2014764712 countsByYear W20147647122015 @default.
• W2014764712 countsByYear W20147647122016 @default.
• W2014764712 countsByYear W20147647122017 @default.
• W2014764712 countsByYear W20147647122018 @default.
• W2014764712 countsByYear W20147647122019 @default.
• W2014764712 countsByYear W20147647122020 @default.
• W2014764712 countsByYear W20147647122021 @default.
• W2014764712 countsByYear W20147647122022 @default.
• W2014764712 countsByYear W20147647122023 @default.
• W2014764712 crossrefType "journal-article" @default.
• W2014764712 hasAuthorship W2014764712A5001667773 @default.
• W2014764712 hasAuthorship W2014764712A5016932546 @default.
• W2014764712 hasAuthorship W2014764712A5055387674 @default.
• W2014764712 hasAuthorship W2014764712A5056006133 @default.
• W2014764712 hasAuthorship W2014764712A5058887915 @default.
• W2014764712 hasAuthorship W2014764712A5059887246 @default.
• W2014764712 hasConcept C105702510 @default.
• W2014764712 hasConcept C12554922 @default.
• W2014764712 hasConcept C136229726 @default.
• W2014764712 hasConcept C142724271 @default.
• W2014764712 hasConcept C153074725 @default.
• W2014764712 hasConcept C153911025 @default.
• W2014764712 hasConcept C185592680 @default.
• W2014764712 hasConcept C197534660 @default.
• W2014764712 hasConcept C203014093 @default.
• W2014764712 hasConcept C204787440 @default.
• W2014764712 hasConcept C2776164576 @default.
• W2014764712 hasConcept C2780550940 @default.
• W2014764712 hasConcept C2781013607 @default.
• W2014764712 hasConcept C3020332539 @default.
• W2014764712 hasConcept C49892992 @default.
• W2014764712 hasConcept C54173615 @default.
• W2014764712 hasConcept C55493867 @default.
• W2014764712 hasConcept C71924100 @default.
• W2014764712 hasConcept C86803240 @default.
• W2014764712 hasConcept C89429830 @default.
• W2014764712 hasConceptScore W2014764712C105702510 @default.
• W2014764712 hasConceptScore W2014764712C12554922 @default.
• W2014764712 hasConceptScore W2014764712C136229726 @default.
• W2014764712 hasConceptScore W2014764712C142724271 @default.
• W2014764712 hasConceptScore W2014764712C153074725 @default.
• W2014764712 hasConceptScore W2014764712C153911025 @default.
• W2014764712 hasConceptScore W2014764712C185592680 @default.
• W2014764712 hasConceptScore W2014764712C197534660 @default.
• W2014764712 hasConceptScore W2014764712C203014093 @default.
• W2014764712 hasConceptScore W2014764712C204787440 @default.

• next