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- W2014765249 abstract "Beclin 1 binds to Bcl-2 through its BH3 domain and this interaction inhibits starvation-induced autophagy. However, we have found that when Beclin 1 binds thus to Bcl-2, it fails to inhibit Bcl-2-mediated protection against four different inducers of apoptosis. In this punctum, we discuss possible reasons why Beclin 1 fails to behave like other BH3-only proteins and induce apoptosis." @default.
- W2014765249 created "2016-06-24" @default.
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- W2014765249 date "2009-08-16" @default.
- W2014765249 modified "2023-09-25" @default.
- W2014765249 title "Why doesn’t Beclin 1, a BH3-only protein, suppress the anti-apoptotic function of Bcl-2?" @default.
- W2014765249 doi "https://doi.org/10.4161/auto.9096" @default.
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