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• W2014767476 abstract "Recent research has proposed that proprioceptive deficits may exist in Parkinson's disease (PD); however, proprioception has not been studied in those who experience freezing of gait (FOG). Proprioception was investigated through stimulation of proprioceptive receptors via patellar tendon vibration. In a force matching task to either 10% or 30% maximal voluntary contraction, response to vibration with and without vision of a force target was compared between 15 PD with FOG (PD-FOG), 16 PD without FOG (PD non-FOG), and 15 non-PD control participants (Controls). In a 15-s trial, vision of the target was provided for the first 10 s but in the last 5 s, four conditions were possible: (i) vision, no vibration; (ii) vision, vibration; (iii) no vision, no vibration; or (iv) no vision, vibration. The expected healthy response to vibration was an overshoot of the target. Controls and PD non-FOG did not perform significantly different with or without: vibration or vision. PD-FOG performed similarly to Controls and PD non-FOG in the baseline condition (i). Errors by PD-FOG on the other conditions (ii–iv) were significantly different from the baseline condition but were not significantly different from each other. The PD-FOG group significantly undershot the target when vibration was added [F(2,36)=4.8376, P<0.02] and when vision was removed [F(2,36)=4.8376, P<0.02]. It is suggested that any deviation from normal sensory availability contributes to severe deficits in PD-FOG." @default.
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• W2014767476 date "2011-09-01" @default.
• W2014767476 modified "2023-09-27" @default.
• W2014767476 title "Proprioceptive deficits in Parkinson's disease patients with freezing of gait" @default.
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• W2014767476 doi "https://doi.org/10.1016/j.neuroscience.2011.06.071" @default.
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