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• W2014776704 abstract "The green credentials of ionic liquids (ILs) are being challenged due to the increasing evidence of their toxicity. The hormetic effects further raised their ecological concern. However, it remained poorly studied on the time-dependent changes of the hormetic effects and the mechanisms. In this study, we investigated the time-dependent hormetic effects of four 1-alkyl-3-methylimidazolium bromide ([amim]Br), including 1-ethyl ([emim]Br), -butyl ([bmim]Br), -hexyl ([hmim]Br) and -octyl ([omim]Br), on the luminescence of Vibrio qinghaiensis sp.-Q67. The results showed that [amim]Br with shorter side chains, [emim]Br and [bmim]Br, caused obvious hormetic time-dependent toxicities. The effective concentration (EC) values for the hormetic effects of [emim]Br and [bmim]Br increased with time. [amim]Br with longer side chains, [hmim]Br and [omim]Br, produced sigmoid concentration-dependent inhibitions on the luminescence, and the EC50 values almost unchanged. To illustrate the mechanism, we subsequently examined the responses of redox reactants and antioxidases. [emim]Br and [bmim]Br significantly induced FMN (flavin mononucleotide), NADH (reduced nicotinamide adenine dinucleotide), SOD (superoxide dismutase) and CAT (catalase), and the inductions increased with time, which is similar to the time-dependent changes of their hormetic effects on Q67. Meanwhile, [hmim]Br and [omim]Br did not cause significant effects on the redox reactants and antioxidases. In conclusion, the hormetic effects of [amim]Br on the luminescence, redox reactants and antioxidases showed the dependence on both exposure time and side chains. Our findings provided insights into the time-dependent biological process of the hormetic effects of [emim]Br and [bmim]Br on the photobacterium and its biochemical indicators." @default.
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• W2014776704 date "2013-04-01" @default.
• W2014776704 modified "2023-10-17" @default.
• W2014776704 title "Time-dependent hormetic effects of 1-alkyl-3-methylimidazolium bromide on Vibrio qinghaiensis sp.-Q67: Luminescence, redox reactants and antioxidases" @default.
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• W2014776704 doi "https://doi.org/10.1016/j.chemosphere.2012.11.070" @default.
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