Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014777113> ?p ?o ?g. }
- W2014777113 endingPage "73" @default.
- W2014777113 startingPage "68" @default.
- W2014777113 abstract "Many molecular epidemiological studies were carried out in recent years to assess the association between the MTHFR C677T polymorphism and migraine risk in diverse populations. However, the results remain controversial rather than conclusive. The objective of this study was to investigate the role of C677T MTHFR polymorphism in migraine pathogenesis. We performed a meta-analysis of published case–control studies concerning the association of the C677T MTHFR polymorphism and migraine. Pooled ORs were established using both random and fixed effects models. This meta-analysis on 17 studies with 8903 cases and 27,637 controls showed that the allele 677T was associated with a significantly increased risk of total migraine in Asians (TT vs. CT + CC: OR = 1.62, 95% CI: 1.13–2.32, PH = 0.573, I2 = 0.0%; T vs. C: OR = 1.18, 95% CI: 1.00–1.40, PH = 0.147, I2 = 44.1%). Similar results were also presented in Asian populations with MA (TT vs. CC: OR = 1.62, 95% CI: 1.11–3.75; TT vs. CT + CC: OR = 2.00, 95% CI: 1.01–3.95; T vs. C: OR = 1.31, 95% CI: 1.02–1.69) without significant heterogeneity. We conclude that the C677T MTHFR polymorphism, responsible for a reduction of the MTHFR activity in folate metabolism, may act as a genetic susceptibility factor for migraine, MA in particular among the subjects of Asian descent." @default.
- W2014777113 created "2016-06-24" @default.
- W2014777113 creator A5012042163 @default.
- W2014777113 creator A5035444136 @default.
- W2014777113 creator A5039201237 @default.
- W2014777113 creator A5040780405 @default.
- W2014777113 creator A5050131248 @default.
- W2014777113 creator A5059927593 @default.
- W2014777113 creator A5063544050 @default.
- W2014777113 creator A5082941113 @default.
- W2014777113 date "2014-01-01" @default.
- W2014777113 modified "2023-10-10" @default.
- W2014777113 title "MTHFR C677T polymorphism and migraine risk: A meta-analysis" @default.
- W2014777113 cites W1567190417 @default.
- W2014777113 cites W1612957780 @default.
- W2014777113 cites W1963663750 @default.
- W2014777113 cites W1973519218 @default.
- W2014777113 cites W1974210258 @default.
- W2014777113 cites W1993569802 @default.
- W2014777113 cites W1995931698 @default.
- W2014777113 cites W1999547384 @default.
- W2014777113 cites W2001125515 @default.
- W2014777113 cites W2017563607 @default.
- W2014777113 cites W2023657005 @default.
- W2014777113 cites W2033546341 @default.
- W2014777113 cites W2036482778 @default.
- W2014777113 cites W2040668975 @default.
- W2014777113 cites W2046417368 @default.
- W2014777113 cites W2056408120 @default.
- W2014777113 cites W2057183501 @default.
- W2014777113 cites W2060076775 @default.
- W2014777113 cites W2067702732 @default.
- W2014777113 cites W2081411431 @default.
- W2014777113 cites W2081533546 @default.
- W2014777113 cites W2083594971 @default.
- W2014777113 cites W2084476052 @default.
- W2014777113 cites W2087196799 @default.
- W2014777113 cites W2090897293 @default.
- W2014777113 cites W2094395084 @default.
- W2014777113 cites W2095677943 @default.
- W2014777113 cites W2107328434 @default.
- W2014777113 cites W2119388811 @default.
- W2014777113 cites W2123700553 @default.
- W2014777113 cites W2123709583 @default.
- W2014777113 cites W2125435699 @default.
- W2014777113 cites W2133071012 @default.
- W2014777113 cites W2134807245 @default.
- W2014777113 cites W2139514338 @default.
- W2014777113 cites W2140293836 @default.
- W2014777113 cites W2142290671 @default.
- W2014777113 cites W2148762723 @default.
- W2014777113 cites W2157683655 @default.
- W2014777113 cites W2157823046 @default.
- W2014777113 cites W2163682820 @default.
- W2014777113 cites W2165715420 @default.
- W2014777113 cites W2168003810 @default.
- W2014777113 cites W2171062435 @default.
- W2014777113 cites W2172179400 @default.
- W2014777113 cites W3157055731 @default.
- W2014777113 cites W4236245800 @default.
- W2014777113 cites W4254203296 @default.
- W2014777113 doi "https://doi.org/10.1016/j.jns.2013.10.008" @default.
- W2014777113 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24183284" @default.
- W2014777113 hasPublicationYear "2014" @default.
- W2014777113 type Work @default.
- W2014777113 sameAs 2014777113 @default.
- W2014777113 citedByCount "35" @default.
- W2014777113 countsByYear W20147771132014 @default.
- W2014777113 countsByYear W20147771132016 @default.
- W2014777113 countsByYear W20147771132017 @default.
- W2014777113 countsByYear W20147771132018 @default.
- W2014777113 countsByYear W20147771132019 @default.
- W2014777113 countsByYear W20147771132020 @default.
- W2014777113 countsByYear W20147771132021 @default.
- W2014777113 countsByYear W20147771132022 @default.
- W2014777113 countsByYear W20147771132023 @default.
- W2014777113 crossrefType "journal-article" @default.
- W2014777113 hasAuthorship W2014777113A5012042163 @default.
- W2014777113 hasAuthorship W2014777113A5035444136 @default.
- W2014777113 hasAuthorship W2014777113A5039201237 @default.
- W2014777113 hasAuthorship W2014777113A5040780405 @default.
- W2014777113 hasAuthorship W2014777113A5050131248 @default.
- W2014777113 hasAuthorship W2014777113A5059927593 @default.
- W2014777113 hasAuthorship W2014777113A5063544050 @default.
- W2014777113 hasAuthorship W2014777113A5082941113 @default.
- W2014777113 hasConcept C104317684 @default.
- W2014777113 hasConcept C107130276 @default.
- W2014777113 hasConcept C126322002 @default.
- W2014777113 hasConcept C149737253 @default.
- W2014777113 hasConcept C180754005 @default.
- W2014777113 hasConcept C2778541695 @default.
- W2014777113 hasConcept C2780942790 @default.
- W2014777113 hasConcept C2992519594 @default.
- W2014777113 hasConcept C43563269 @default.
- W2014777113 hasConcept C54355233 @default.
- W2014777113 hasConcept C71924100 @default.
- W2014777113 hasConcept C86803240 @default.
- W2014777113 hasConcept C90924648 @default.