Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014782289> ?p ?o ?g. }
Showing items 1 to 59 of
59
with 100 items per page.
- W2014782289 endingPage "120" @default.
- W2014782289 startingPage "113" @default.
- W2014782289 abstract "In rats whose endogenous pituitary secretion had been depressed by phenobarbital and raised ambient temperature (34 C), increases of 131I levels in blood were measured following intrapituitary infusion (4.5–7 μl/hr for 2.5–3 hr) of extracts prepared from the hypothalami of rats and sheep. It was shown that the intrapituitary infusion technique was a sensitive method for testing thyrotropin-releasing factor (TRF) activity provided precautions were taken to prevent cytolysis due to faulty pH or tonicity of the solutions infused. Intrapituitary infusion of dialyzed extracts of rat hypothalamus and of stalk-median eminence (SME) and hypothalamic fragments from sheep at different dosages showed that the magnitude of the response increased with increasing dosage. Intrapituitary infusions of saline or intravenous infusions of sheep hypothalamic extract did not increase blood 131I levels, indicating that neither pituitary damage due to infusion nor TSH contamination of the extracts was responsible for the results. In the sheep, the concentration of TRF in the SME was approximately twice that in the hypothalamus but the latter contained 7 times as much TRF. When compared with 131I responses obtained from intravenous infusion of TSH at 3 dose levels, it was estimated that intrapituitary infusions of TRF in this experiment released only about 5 % of the TSH present in the pituitary store. (Endocrinology81: 113,1967)" @default.
- W2014782289 created "2016-06-24" @default.
- W2014782289 creator A5026481162 @default.
- W2014782289 creator A5058150541 @default.
- W2014782289 date "1967-07-01" @default.
- W2014782289 modified "2023-09-25" @default.
- W2014782289 title "Elevation of Thyrotropin Release by Intrapituitary Infusion of Crude Hypothalamic Extracts" @default.
- W2014782289 cites W1991536033 @default.
- W2014782289 doi "https://doi.org/10.1210/endo-81-1-113" @default.
- W2014782289 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6027409" @default.
- W2014782289 hasPublicationYear "1967" @default.
- W2014782289 type Work @default.
- W2014782289 sameAs 2014782289 @default.
- W2014782289 citedByCount "12" @default.
- W2014782289 crossrefType "journal-article" @default.
- W2014782289 hasAuthorship W2014782289A5026481162 @default.
- W2014782289 hasAuthorship W2014782289A5058150541 @default.
- W2014782289 hasConcept C117277713 @default.
- W2014782289 hasConcept C126322002 @default.
- W2014782289 hasConcept C134018914 @default.
- W2014782289 hasConcept C176685330 @default.
- W2014782289 hasConcept C185592680 @default.
- W2014782289 hasConcept C2777003273 @default.
- W2014782289 hasConcept C2777658017 @default.
- W2014782289 hasConcept C2779067335 @default.
- W2014782289 hasConcept C71315377 @default.
- W2014782289 hasConcept C71924100 @default.
- W2014782289 hasConceptScore W2014782289C117277713 @default.
- W2014782289 hasConceptScore W2014782289C126322002 @default.
- W2014782289 hasConceptScore W2014782289C134018914 @default.
- W2014782289 hasConceptScore W2014782289C176685330 @default.
- W2014782289 hasConceptScore W2014782289C185592680 @default.
- W2014782289 hasConceptScore W2014782289C2777003273 @default.
- W2014782289 hasConceptScore W2014782289C2777658017 @default.
- W2014782289 hasConceptScore W2014782289C2779067335 @default.
- W2014782289 hasConceptScore W2014782289C71315377 @default.
- W2014782289 hasConceptScore W2014782289C71924100 @default.
- W2014782289 hasIssue "1" @default.
- W2014782289 hasLocation W20147822891 @default.
- W2014782289 hasLocation W20147822892 @default.
- W2014782289 hasOpenAccess W2014782289 @default.
- W2014782289 hasPrimaryLocation W20147822891 @default.
- W2014782289 hasRelatedWork W1985729391 @default.
- W2014782289 hasRelatedWork W2002922135 @default.
- W2014782289 hasRelatedWork W2005359107 @default.
- W2014782289 hasRelatedWork W2029486896 @default.
- W2014782289 hasRelatedWork W2036485448 @default.
- W2014782289 hasRelatedWork W2037244247 @default.
- W2014782289 hasRelatedWork W2057790389 @default.
- W2014782289 hasRelatedWork W2066173879 @default.
- W2014782289 hasRelatedWork W2074358091 @default.
- W2014782289 hasRelatedWork W2116906034 @default.
- W2014782289 hasVolume "81" @default.
- W2014782289 isParatext "false" @default.
- W2014782289 isRetracted "false" @default.
- W2014782289 magId "2014782289" @default.
- W2014782289 workType "article" @default.