Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014823364> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W2014823364 endingPage "888" @default.
- W2014823364 startingPage "883" @default.
- W2014823364 abstract "Acylgalactosylceramides (AGC) from forebrains of normal and dysmyelinating (quaking and shiverer) mice were purified by Florisil column chromatography and preparative TLC. These procedures resolved the AGC on the basis of their Rf values into two main fractions which co-nigrate with their homologs from rat forebrains. In control animals, AGC were detectable in mouse forebrains from the eighth postnatal day and reached maximal values within 20 days. The same developmental pattern was obtained in dysmyelinating shiverer mice but the AGC content was reduced to approximately 30% of control values. In quaking mutants, the AGC were hardly detected. They were also present in sciatic nerve of normal mice and to a lesser extent in trembler mice. Gas chromatography-mass spectrometry analysis of both ester- and amide-linked fatty acids isolated from AGC of normal and shiverer mice shows that the shiverer mutant AGC display a chemical structure similar to that of normal AGC. AGC constituents of control myelin are reduced by approximately 70% in shiverer myelin, indicating that these molecules can be considered as early markers of oligodendrocyte differentiation. The early arrest of myelinogenesis in the quaking animals and the near absence of AGC are in good agreement with this proposal. Moreover, the reduced amount of AGC in the trembler PNS indicates that AGC could also be early markers for differentiation of the Schwann cell." @default.
- W2014823364 created "2016-06-24" @default.
- W2014823364 creator A5010037338 @default.
- W2014823364 creator A5016544417 @default.
- W2014823364 creator A5026873608 @default.
- W2014823364 creator A5037746077 @default.
- W2014823364 creator A5046388663 @default.
- W2014823364 creator A5062555831 @default.
- W2014823364 date "1988-03-01" @default.
- W2014823364 modified "2023-09-27" @default.
- W2014823364 title "Acylgalactosylceramides in Developing Dysmyelinating Mutant Mice" @default.
- W2014823364 cites W1494947280 @default.
- W2014823364 cites W1522247502 @default.
- W2014823364 cites W1777180563 @default.
- W2014823364 cites W1855721896 @default.
- W2014823364 cites W1872873041 @default.
- W2014823364 cites W1964967794 @default.
- W2014823364 cites W1965923347 @default.
- W2014823364 cites W1966783765 @default.
- W2014823364 cites W1979779046 @default.
- W2014823364 cites W1994096971 @default.
- W2014823364 cites W2012480637 @default.
- W2014823364 cites W2022791658 @default.
- W2014823364 cites W2026730278 @default.
- W2014823364 cites W2027063762 @default.
- W2014823364 cites W2040153417 @default.
- W2014823364 cites W2045794009 @default.
- W2014823364 cites W2052528465 @default.
- W2014823364 cites W2074392865 @default.
- W2014823364 cites W2080999627 @default.
- W2014823364 cites W2119216843 @default.
- W2014823364 cites W2122492161 @default.
- W2014823364 cites W2148448141 @default.
- W2014823364 cites W2168526937 @default.
- W2014823364 cites W27694750 @default.
- W2014823364 cites W3202597652 @default.
- W2014823364 cites W4239772442 @default.
- W2014823364 doi "https://doi.org/10.1111/j.1471-4159.1988.tb02995.x" @default.
- W2014823364 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3339361" @default.
- W2014823364 hasPublicationYear "1988" @default.
- W2014823364 type Work @default.
- W2014823364 sameAs 2014823364 @default.
- W2014823364 citedByCount "3" @default.
- W2014823364 crossrefType "journal-article" @default.
- W2014823364 hasAuthorship W2014823364A5010037338 @default.
- W2014823364 hasAuthorship W2014823364A5016544417 @default.
- W2014823364 hasAuthorship W2014823364A5026873608 @default.
- W2014823364 hasAuthorship W2014823364A5037746077 @default.
- W2014823364 hasAuthorship W2014823364A5046388663 @default.
- W2014823364 hasAuthorship W2014823364A5062555831 @default.
- W2014823364 hasConcept C104317684 @default.
- W2014823364 hasConcept C134018914 @default.
- W2014823364 hasConcept C143065580 @default.
- W2014823364 hasConcept C153911025 @default.
- W2014823364 hasConcept C185592680 @default.
- W2014823364 hasConcept C2776985911 @default.
- W2014823364 hasConcept C2778609137 @default.
- W2014823364 hasConcept C2780064007 @default.
- W2014823364 hasConcept C529278444 @default.
- W2014823364 hasConcept C55493867 @default.
- W2014823364 hasConcept C86803240 @default.
- W2014823364 hasConcept C95444343 @default.
- W2014823364 hasConceptScore W2014823364C104317684 @default.
- W2014823364 hasConceptScore W2014823364C134018914 @default.
- W2014823364 hasConceptScore W2014823364C143065580 @default.
- W2014823364 hasConceptScore W2014823364C153911025 @default.
- W2014823364 hasConceptScore W2014823364C185592680 @default.
- W2014823364 hasConceptScore W2014823364C2776985911 @default.
- W2014823364 hasConceptScore W2014823364C2778609137 @default.
- W2014823364 hasConceptScore W2014823364C2780064007 @default.
- W2014823364 hasConceptScore W2014823364C529278444 @default.
- W2014823364 hasConceptScore W2014823364C55493867 @default.
- W2014823364 hasConceptScore W2014823364C86803240 @default.
- W2014823364 hasConceptScore W2014823364C95444343 @default.
- W2014823364 hasIssue "3" @default.
- W2014823364 hasLocation W20148233641 @default.
- W2014823364 hasLocation W20148233642 @default.
- W2014823364 hasOpenAccess W2014823364 @default.
- W2014823364 hasPrimaryLocation W20148233641 @default.
- W2014823364 hasRelatedWork W149510724 @default.
- W2014823364 hasRelatedWork W1776225985 @default.
- W2014823364 hasRelatedWork W1992272763 @default.
- W2014823364 hasRelatedWork W2015139023 @default.
- W2014823364 hasRelatedWork W2023693164 @default.
- W2014823364 hasRelatedWork W2033630325 @default.
- W2014823364 hasRelatedWork W2042832329 @default.
- W2014823364 hasRelatedWork W2064187043 @default.
- W2014823364 hasRelatedWork W2186256270 @default.
- W2014823364 hasRelatedWork W2231041323 @default.
- W2014823364 hasVolume "50" @default.
- W2014823364 isParatext "false" @default.
- W2014823364 isRetracted "false" @default.
- W2014823364 magId "2014823364" @default.
- W2014823364 workType "article" @default.