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- W2014842255 abstract "Mitochondrial responses to ischemic stress play an important role in necrosis and apoptosis of brain cells. Recent studies using several different experimental preparations have shown that activation of ATP-sensitive potassium channels in mitochondria (mitoKATP channels) is able to protect neurons and astroglia against injury and death. Thus, targeting of mitoKATP channels appears to be a novel approach to neuroprotection. However, little is known about the mechanisms involved. The purpose of this review is to detail the current state of knowledge about this important, emerging area of investigation, and to provide suggestions for future studies." @default.
- W2014842255 created "2016-06-24" @default.
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- W2014842255 date "2004-11-01" @default.
- W2014842255 modified "2023-10-15" @default.
- W2014842255 title "Targeting mitochondrial ATP-sensitive potassium channels—a novel approach to neuroprotection" @default.
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- W2014842255 doi "https://doi.org/10.1016/j.brainresrev.2004.06.011" @default.
- W2014842255 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15571770" @default.
- W2014842255 hasPublicationYear "2004" @default.
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