FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014862284> ?p ?o ?g. }

• W2014862284 endingPage "905" @default.
• W2014862284 startingPage "896" @default.
• W2014862284 abstract "Embryo production is a useful tool for ex situ conservation of endangered species and breeds, despite a high variability in the ovarian response to superovulatory treatments. The current study evaluated the incidence and mechanisms of genetic factors in such variability, by determining the pharmacokinetics and pharmacodynamics of a standard treatment with ovine FSH (oFSH) in two endangered Spanish sheep breeds (Rubia del Molar, R, and Negra de Colmenar, N) in comparison to Manchega ewes (M, control group). In the first experiment, pharmacokinetics of an i.m. single dose of 1.32 mg of oFSH was evaluated in seven animals of each breed. Plasma FSH concentrations reached their maximum at 4 h post-administration in all the ewes, but several of the kinetic parameters (plasma FSH concentration at 4 h post-administration, maximum plasma FSH concentration, Cmax, and both the area under the plasma concentration-time curve extrapolated to the infinite, AUCinf, and to the last moment of sampling, AUClast) were higher in the N group. In the second trial, 10 animals of each breed were superovulated using eight decreasing doses of oFSH (3× 1.32 mg, 2× 1.10 mg, and 3× 0.88 mg). The R group, when compared to N and M, showed both a higher number of corpora lutea (13.7 ± 0.6 versus 10.0 ± 0.4 in N and 9.8 ± 0.6 in M, P < 0.05 for both) and embryos (7.9 ± 0.8 versus 4.3 ± 0.4 in N, P < 0.05, and 6.7 ± 0.5 in M, n.s.). Evaluation of pharmacokinetic and dynamic parameters showed that, although there was a trend for a higher hormone availability in R sheep, mean FSH plasma concentrations were similar between breeds (0.54 ± 0.08 ng/ml for R, 0.45 ± 0.05 ng/ml for N and 0.35 ± 0.05 ng/ml for M). However, differences were found in the number of preovulatory follicles growing in response to the FSH treatment between R (24.4 ± 2.2), M (18.9 ± 1.5, n.s.) and N sheep (14.1 ± 1.4; P < 0.01). Thus, differences in embryo yields between breeds would be related to differences in the pattern of follicular growth in response to FSH treatment." @default.
• W2014862284 created "2016-06-24" @default.
• W2014862284 creator A5016049495 @default.
• W2014862284 creator A5034148172 @default.
• W2014862284 creator A5039318627 @default.
• W2014862284 creator A5039781020 @default.
• W2014862284 creator A5045377873 @default.
• W2014862284 creator A5046912687 @default.
• W2014862284 creator A5052065231 @default.
• W2014862284 creator A5061696936 @default.
• W2014862284 creator A5076303288 @default.
• W2014862284 date "2006-09-01" @default.
• W2014862284 modified "2023-10-18" @default.
• W2014862284 title "Effects of breed on kinetics of ovine FSH and ovarian response in superovulated sheep" @default.
• W2014862284 cites W1966595045 @default.
• W2014862284 cites W1967808459 @default.
• W2014862284 cites W1971223259 @default.
• W2014862284 cites W1974769257 @default.
• W2014862284 cites W1979422598 @default.
• W2014862284 cites W1985824682 @default.
• W2014862284 cites W1994513157 @default.
• W2014862284 cites W2000915587 @default.
• W2014862284 cites W2000994252 @default.
• W2014862284 cites W2002742451 @default.
• W2014862284 cites W2008369054 @default.
• W2014862284 cites W2024390269 @default.
• W2014862284 cites W2025364227 @default.
• W2014862284 cites W2029314135 @default.
• W2014862284 cites W2029544442 @default.
• W2014862284 cites W2030561813 @default.
• W2014862284 cites W2031081000 @default.
• W2014862284 cites W2032008101 @default.
• W2014862284 cites W2050657850 @default.
• W2014862284 cites W2050874941 @default.
• W2014862284 cites W2052411636 @default.
• W2014862284 cites W2071407188 @default.
• W2014862284 cites W2073859633 @default.
• W2014862284 cites W2077751211 @default.
• W2014862284 cites W2079641290 @default.
• W2014862284 cites W2107383506 @default.
• W2014862284 cites W2115657213 @default.
• W2014862284 cites W2118510876 @default.
• W2014862284 cites W2118785393 @default.
• W2014862284 cites W2134314536 @default.
• W2014862284 cites W2155864658 @default.
• W2014862284 cites W233799810 @default.
• W2014862284 cites W4229573432 @default.
• W2014862284 doi "https://doi.org/10.1016/j.theriogenology.2006.02.024" @default.
• W2014862284 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16580718" @default.
• W2014862284 hasPublicationYear "2006" @default.
• W2014862284 type Work @default.
• W2014862284 sameAs 2014862284 @default.
• W2014862284 citedByCount "26" @default.
• W2014862284 countsByYear W20148622842012 @default.
• W2014862284 countsByYear W20148622842013 @default.
• W2014862284 countsByYear W20148622842014 @default.
• W2014862284 countsByYear W20148622842015 @default.
• W2014862284 countsByYear W20148622842016 @default.
• W2014862284 countsByYear W20148622842019 @default.
• W2014862284 countsByYear W20148622842020 @default.
• W2014862284 countsByYear W20148622842022 @default.
• W2014862284 countsByYear W20148622842023 @default.
• W2014862284 crossrefType "journal-article" @default.
• W2014862284 hasAuthorship W2014862284A5016049495 @default.
• W2014862284 hasAuthorship W2014862284A5034148172 @default.
• W2014862284 hasAuthorship W2014862284A5039318627 @default.
• W2014862284 hasAuthorship W2014862284A5039781020 @default.
• W2014862284 hasAuthorship W2014862284A5045377873 @default.
• W2014862284 hasAuthorship W2014862284A5046912687 @default.
• W2014862284 hasAuthorship W2014862284A5052065231 @default.
• W2014862284 hasAuthorship W2014862284A5061696936 @default.
• W2014862284 hasAuthorship W2014862284A5076303288 @default.
• W2014862284 hasConcept C111113717 @default.
• W2014862284 hasConcept C112705442 @default.
• W2014862284 hasConcept C126322002 @default.
• W2014862284 hasConcept C134018914 @default.
• W2014862284 hasConcept C140793950 @default.
• W2014862284 hasConcept C196843134 @default.
• W2014862284 hasConcept C22979827 @default.
• W2014862284 hasConcept C2776482104 @default.
• W2014862284 hasConcept C3020079912 @default.
• W2014862284 hasConcept C54355233 @default.
• W2014862284 hasConcept C71924100 @default.
• W2014862284 hasConcept C86803240 @default.
• W2014862284 hasConcept C98274493 @default.
• W2014862284 hasConceptScore W2014862284C111113717 @default.
• W2014862284 hasConceptScore W2014862284C112705442 @default.
• W2014862284 hasConceptScore W2014862284C126322002 @default.
• W2014862284 hasConceptScore W2014862284C134018914 @default.
• W2014862284 hasConceptScore W2014862284C140793950 @default.
• W2014862284 hasConceptScore W2014862284C196843134 @default.
• W2014862284 hasConceptScore W2014862284C22979827 @default.
• W2014862284 hasConceptScore W2014862284C2776482104 @default.
• W2014862284 hasConceptScore W2014862284C3020079912 @default.
• W2014862284 hasConceptScore W2014862284C54355233 @default.
• W2014862284 hasConceptScore W2014862284C71924100 @default.
• W2014862284 hasConceptScore W2014862284C86803240 @default.
• W2014862284 hasConceptScore W2014862284C98274493 @default.

• next