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- W2014862340 abstract "The sterol composition of the sponge Dysidea fragilis, coming from the lagoon of Venice, has been investigated; our results confirmed the variability of D. fragilis biochemistry. The sponge elaborates, in addition to eight usual 3β-hydroxy sterols, thirteen polyhydroxysterols, eight of them (6–13) were novel compounds. Their structures were established by spectroscopic data. New compounds 3β,5α,6β,7α-tetrahydroxy-cholest-8(9)-en-11-one (8), 3β,5α,6α-trihydroxy-9,11-secocholest-7-en-9-one (9) and 3β,5α,6α,9α-tetrahydroxy-cholest-7-ene-6-sulfate (11) were proved to be cytotoxic on two different tumor cell lines in vitro." @default.
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- W2014862340 date "1995-10-01" @default.
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- W2014862340 title "New cytotoxic steroids from the marine sponge Dysidea fragilis coming from the lagoon of Venice" @default.
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- W2014862340 doi "https://doi.org/10.1016/0039-128x(95)00055-u" @default.
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