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- W2014863491 abstract "Quenching in liquid scintillation counting causes a decreased counting efficiency and a shift in the radionuclide pulse height distribution. This pulse height shift is toward lower counting windows and gives an apparent decrease in the decay energy of the radionuclide. It is necessary to adjust the counting windows to compensate for this pulse height shift in order to achieve optimum counting conditions. This results in a more accurate answer in a shorter period of time. This compensation is most critical when counting low activity or dual label samples. With low activity samples, the background count rate and its statistical accuracy must be considered when calculating the count rate of the sample. By adjusting the counting windows properly, the background can be minimized without sacrificing counting efficiency (optimum 12/B). In dual label samples there is always some percent of the higher energy radionuclide which contributes to the count rate in the lower energy radionuclide window. The percent of this spillover increases with increasing quench. This can lead to large errors in the dpm calculations. By adjusting the radionuclide counting windows according to the degree of quench, the percent spillover is kept at a minimum while maintaining the highest possible counting efficiency. This results in more accurate dpm values for both radionuclides." @default.
- W2014863491 created "2016-06-24" @default.
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- W2014863491 date "1980-01-01" @default.
- W2014863491 modified "2023-09-26" @default.
- W2014863491 title "The use of optimum window settings in liquid scintillation counting" @default.
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- W2014863491 doi "https://doi.org/10.1016/0020-708x(80)90168-4" @default.
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