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• W2014878032 abstract "The benzodiazepine antagonist Ro 15-1788 has been reported to suppress paired pulse inhibition in the hippocampal slice. It is now shown that the depression of orthodromic synaptic transmission by Ro 15-1788 can be prevented by the adenosine antagonist 8-phenyl-theophylline, or by adenosine deaminase. Since Ro 15-1788 has previously been shown to inhibit adenosine-uptake into rat brain tissue, it is suggested that this property, leading to an accumulation of extracellular adenosine, may underlie its effects on synaptic transmission." @default.
• W2014878032 created "2016-06-24" @default.
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• W2014878032 date "1986-08-01" @default.
• W2014878032 modified "2023-09-25" @default.
• W2014878032 title "The suppression of hippocampal potentials by the benzodiazepine antagonist Ro 15-1788 may be mediated by purines" @default.
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• W2014878032 doi "https://doi.org/10.1016/0006-8993(86)90240-4" @default.
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