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- W2014885265 abstract "Whilst studying the effects of pro-opiomelanocortin (POMC) peptides on adrenocortical steroidogenesis we showed that α-melanocyte-stimulating hormone (α-MSH) has a specific glomerulotropic effect and potentiates both the mineralocorticotropic and glucocorticotropic effects of ACTH. The fragments ACTH-(4–10) and ACTH-(11–13) are responsible for the glomerulotropic effect of α-MSH. ß-Endorphin enhances, inhibits or has no effect on corticosteroidogenesis, depending on the dose and on the functional state of the adrenocortical cells (saturation of the receptors). ß-Endorphin antagonizes the effect of α-MSH on aldosterone production. It is suggested that the modulatory effects of POMC peptides on adrenocortical steroidogenesis may be of physiological significance." @default.
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- W2014885265 date "1993-04-01" @default.
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- W2014885265 title "Effects of pro-opiomelanocortin peptides on adrenocortical steroidogenesis" @default.
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- W2014885265 doi "https://doi.org/10.1016/0960-0760(93)90133-h" @default.
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