Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014893669> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2014893669 endingPage "324" @default.
- W2014893669 startingPage "324" @default.
- W2014893669 abstract "Neuromyelitis optica (NMO) is an inflammatory disease of the optic nerves and spinal cord that leads to blindness and paralysis. Effective immunosuppression is the standard of care for relapse prevention.To compare the relapse and treatment failure rates among patients receiving the 3 most common forms of immunosuppression for NMO: azathioprine, mycophenolate mofetil, and rituximab.We performed a retrospective, multicenter analysis of relapses in 90 patients with NMO and NMO spectrum disorder treated with azathioprine, mycophenolate, and/or rituximab at the Mayo Clinic and the Johns Hopkins Hospital during the past 10 years.Annualized relapse rates.Rituximab reduced the relapse rate up to 88.2%, with 2 in 3 patients achieving complete remission. Mycophenolate reduced the relapse rate by up to 87.4%, with a 36% failure rate. Azathioprine reduced the relapse rate by 72.1% but had a 53% failure rate despite concurrent use of prednisone.Initial treatment with rituximab, mycophenolate, and, to a lesser degree, azathioprine significantly reduces relapse rates in NMO and NMO spectrum disorder patients. Patients for whom initial treatment fails often achieve remission when treatment is switched from one to another of these drugs." @default.
- W2014893669 created "2016-06-24" @default.
- W2014893669 creator A5000669492 @default.
- W2014893669 creator A5000750171 @default.
- W2014893669 creator A5006100482 @default.
- W2014893669 creator A5008002660 @default.
- W2014893669 creator A5027362230 @default.
- W2014893669 date "2014-03-01" @default.
- W2014893669 modified "2023-10-14" @default.
- W2014893669 title "Comparison of Relapse and Treatment Failure Rates Among Patients With Neuromyelitis Optica" @default.
- W2014893669 cites W1984449814 @default.
- W2014893669 cites W2007556864 @default.
- W2014893669 cites W2021279859 @default.
- W2014893669 cites W2023686387 @default.
- W2014893669 cites W2029012161 @default.
- W2014893669 cites W2045939196 @default.
- W2014893669 cites W2057654369 @default.
- W2014893669 cites W2079409038 @default.
- W2014893669 cites W2114360739 @default.
- W2014893669 cites W2125096061 @default.
- W2014893669 cites W2129933277 @default.
- W2014893669 cites W2130342500 @default.
- W2014893669 cites W2133934007 @default.
- W2014893669 cites W2136132690 @default.
- W2014893669 cites W2150598981 @default.
- W2014893669 doi "https://doi.org/10.1001/jamaneurol.2013.5699" @default.
- W2014893669 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24445513" @default.
- W2014893669 hasPublicationYear "2014" @default.
- W2014893669 type Work @default.
- W2014893669 sameAs 2014893669 @default.
- W2014893669 citedByCount "244" @default.
- W2014893669 countsByYear W20148936692014 @default.
- W2014893669 countsByYear W20148936692015 @default.
- W2014893669 countsByYear W20148936692016 @default.
- W2014893669 countsByYear W20148936692017 @default.
- W2014893669 countsByYear W20148936692018 @default.
- W2014893669 countsByYear W20148936692019 @default.
- W2014893669 countsByYear W20148936692020 @default.
- W2014893669 countsByYear W20148936692021 @default.
- W2014893669 countsByYear W20148936692022 @default.
- W2014893669 countsByYear W20148936692023 @default.
- W2014893669 crossrefType "journal-article" @default.
- W2014893669 hasAuthorship W2014893669A5000669492 @default.
- W2014893669 hasAuthorship W2014893669A5000750171 @default.
- W2014893669 hasAuthorship W2014893669A5006100482 @default.
- W2014893669 hasAuthorship W2014893669A5008002660 @default.
- W2014893669 hasAuthorship W2014893669A5027362230 @default.
- W2014893669 hasConcept C126322002 @default.
- W2014893669 hasConcept C141071460 @default.
- W2014893669 hasConcept C203014093 @default.
- W2014893669 hasConcept C2776694085 @default.
- W2014893669 hasConcept C2776755627 @default.
- W2014893669 hasConcept C2776760755 @default.
- W2014893669 hasConcept C2778720950 @default.
- W2014893669 hasConcept C2779134260 @default.
- W2014893669 hasConcept C2779338263 @default.
- W2014893669 hasConcept C2780252810 @default.
- W2014893669 hasConcept C2780640218 @default.
- W2014893669 hasConcept C2780653079 @default.
- W2014893669 hasConcept C2781137167 @default.
- W2014893669 hasConcept C71924100 @default.
- W2014893669 hasConceptScore W2014893669C126322002 @default.
- W2014893669 hasConceptScore W2014893669C141071460 @default.
- W2014893669 hasConceptScore W2014893669C203014093 @default.
- W2014893669 hasConceptScore W2014893669C2776694085 @default.
- W2014893669 hasConceptScore W2014893669C2776755627 @default.
- W2014893669 hasConceptScore W2014893669C2776760755 @default.
- W2014893669 hasConceptScore W2014893669C2778720950 @default.
- W2014893669 hasConceptScore W2014893669C2779134260 @default.
- W2014893669 hasConceptScore W2014893669C2779338263 @default.
- W2014893669 hasConceptScore W2014893669C2780252810 @default.
- W2014893669 hasConceptScore W2014893669C2780640218 @default.
- W2014893669 hasConceptScore W2014893669C2780653079 @default.
- W2014893669 hasConceptScore W2014893669C2781137167 @default.
- W2014893669 hasConceptScore W2014893669C71924100 @default.
- W2014893669 hasIssue "3" @default.
- W2014893669 hasLocation W20148936691 @default.
- W2014893669 hasLocation W20148936692 @default.
- W2014893669 hasOpenAccess W2014893669 @default.
- W2014893669 hasPrimaryLocation W20148936691 @default.
- W2014893669 hasRelatedWork W1859082783 @default.
- W2014893669 hasRelatedWork W2009114633 @default.
- W2014893669 hasRelatedWork W2014893669 @default.
- W2014893669 hasRelatedWork W2037116344 @default.
- W2014893669 hasRelatedWork W2041786891 @default.
- W2014893669 hasRelatedWork W2060834223 @default.
- W2014893669 hasRelatedWork W2123369314 @default.
- W2014893669 hasRelatedWork W2137080874 @default.
- W2014893669 hasRelatedWork W2150598981 @default.
- W2014893669 hasRelatedWork W2169974863 @default.
- W2014893669 hasVolume "71" @default.
- W2014893669 isParatext "false" @default.
- W2014893669 isRetracted "false" @default.
- W2014893669 magId "2014893669" @default.
- W2014893669 workType "article" @default.