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- W2014897050 abstract "The suitability of newborn pig skin as an alternative to human epidermis in in vitro permeation studies was investigated. A set of 7 benzoxazinones was used to perform in vitro experiments by using a modified Franz diffusion cell and excised newborn pig skin as a membrane. The maximum flux through newborn pig skin (Jmax,p) was compared with the maximum flux through excised human epidermis (Jmax,h), available from the literature, by means of the factor of difference value FoD=Jmax,p/Jmax,h. The FoD values ranged from 0.48 to 1.91, indicating thatJmax,p andJmax,h were in the same order of magnitude." @default.
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- W2014897050 date "2007-10-01" @default.
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- W2014897050 title "Newborn pig skin as model membrane in in vitro drug permeation studies: A technical note" @default.
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- W2014897050 doi "https://doi.org/10.1208/pt0804094" @default.
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