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- W2014914436 abstract "Binding of immunoglobulin G, fibrinogen and fibronectin to 112 cultures of coagulase-positive staphylococci together with 7 of coagulase-negative S. hyicus subsp. chromogenes were investigated. Of the coagulase-positive staphylococcal cultures 45 were S. hyicus subsp. hyicus, 51 S. intermedius and 16 S. aureus. All 45 S. hyicus subsp. hyicus cultures coagulated plasma preparations from pigs and not always those from sheep, rabbits and dogs. Labelled IgG was bound by all cultures of S. hyicus subsp. hyicus and S. aureus, but only by 6 of 51 S. intermedius cultures. Fibrinogen interacted with 28 of the 45 S. hyicus subsp. hyicus cultures, with 17 of the 51 S. intermedius cultures and with S. aureus throughout. Fibronectin reacted with 19 cultures of S. hyicus subsp. hyicus, 11 of S. intermedius and all S. aureus. The binding activities for labelled IgG were more pronounced than those for fibrinogen and fibronectin. None of the 7 cultures of S. hyicus subsp. chromogenes bound any of these plasma proteins. Bindings of fibrinogen and fibronectin to S. hyicus subsp. hyicus and S. intermedius elicited only in part distinct clumping reactions of the staphylococci in the respective plasma proteins. In der vorliegenden Arbeit wurde die Bindung der Plasmaproteine Immunoglobulin G, Fibrinogen und Fibronektin an 112 Koagulase-positive Staphylokokkenkulturen und an 7 Koagulase-negative S. hyicus subsp. chromogenes untersucht. Unter den Koagulase-positiven Kulturen waren 45 S. hyicus subsp. hyicus, 51 S. intermedius und 16 S. aureus. Alle 45 S. hyicus subsp. hyicus waren in Plasmapräparationen des Schweines Koagulase-positiv und nur zu einem geringeren Teil in Plasmen von Schaf, Kaninchen und Hund. Alle Kulturen von S. hyicus subsp. hyicus und S. aureus sowie 6 von 51 S. intermedius-Kulturen banden radioaktiv markiertes IgG. Fibrinogen wurde von 28 der S. hyicus subsp. hyicus-Kulturen, 17 der 51 S. intermedius-Kulturen und allen S. aureus gebunden. Fibronektin reagierte mit 19 Kulturen von S. hyicus subsp. hyicus, 11 S. intermedius und allen S. aureus. Radioaktiv markiertes IgG wies im Vergleich zu markiertem Fibrinogen und Fibronektin deutlich höhere Bindungsaktivitäten auf. Bei keiner der untersuchten 7 S. hyicus subsp. chromogenes-Kulturen konnte eine Bindung von Plasmaproteinen nachgewiesen werden. Die Bindungen von Fibrinogen und Fibronektin an S. hyicus subsp. hyicus-Kulturen und an S. intermedius wiesen nur teilweise eine Beziehung zu der entsprechenden Fibrinogen- oder Fibronektin-Verklumpungsreaktion auf." @default.
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- W2014914436 date "1985-10-01" @default.
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- W2014914436 title "Interactions of Immunoglobulin G, Fibrinogen and Fibronectin with Staphylococcus hyicus and Staphylococcus intermedius" @default.
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- W2014914436 doi "https://doi.org/10.1016/s0176-6724(85)80119-x" @default.
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