FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014920226> ?p ?o ?g. }

• W2014920226 endingPage "417" @default.
• W2014920226 startingPage "414" @default.
• W2014920226 abstract "Increasing cerebral vascular resistance and brain perfusion failure occur within 90 minutes following cardiac arrest and resuscitation. This study followed cortical perfusion for 18 hours after a 15-minute cardiac arrest. Six dogs were anesthetized with ketamine and gallamine and then mechanically ventilated. They were instrumented for arterial pressure, central venous pressure, and regional cerebral cortical blood flow (rCCBF) determined by thermodilution. A left thoracotomy and pericardiotomy were done. Two dogs served as non-arrest controls. Cardiac arrest was produced in four dogs with an intravenous bolus of KC1 at 1 mEq/kg. After 15 minutes of cardiac arrest, the animals were resuscitated with internal massage, NaHCO3, epinephrine, and internal defibrillation. Cortical blood flow was followed for 18 hours. Arterial core temperature was never less than 35 C. Pre-arrest cortical blood flows were 0.86 cc/min/g (± 0.11). The two control animals had stable rCCBF (0.74 ± 0.17) for all determinations during the 18-hour follow-up period. Determinations of rCCBF from 6 to 18 hours in post-arrest animals were 7% to 14% of pre-arrest values. We conclude that the post-resuscitation perfusion failure in the cortex is prolonged. Any potential for neuronal recovery, unless perfusion is protected, would not be realized given this phenomenon. Increasing cerebral vascular resistance and brain perfusion failure occur within 90 minutes following cardiac arrest and resuscitation. This study followed cortical perfusion for 18 hours after a 15-minute cardiac arrest. Six dogs were anesthetized with ketamine and gallamine and then mechanically ventilated. They were instrumented for arterial pressure, central venous pressure, and regional cerebral cortical blood flow (rCCBF) determined by thermodilution. A left thoracotomy and pericardiotomy were done. Two dogs served as non-arrest controls. Cardiac arrest was produced in four dogs with an intravenous bolus of KC1 at 1 mEq/kg. After 15 minutes of cardiac arrest, the animals were resuscitated with internal massage, NaHCO3, epinephrine, and internal defibrillation. Cortical blood flow was followed for 18 hours. Arterial core temperature was never less than 35 C. Pre-arrest cortical blood flows were 0.86 cc/min/g (± 0.11). The two control animals had stable rCCBF (0.74 ± 0.17) for all determinations during the 18-hour follow-up period. Determinations of rCCBF from 6 to 18 hours in post-arrest animals were 7% to 14% of pre-arrest values. We conclude that the post-resuscitation perfusion failure in the cortex is prolonged. Any potential for neuronal recovery, unless perfusion is protected, would not be realized given this phenomenon." @default.
• W2014920226 created "2016-06-24" @default.
• W2014920226 creator A5005962993 @default.
• W2014920226 creator A5011056310 @default.
• W2014920226 creator A5016620154 @default.
• W2014920226 creator A5024880747 @default.
• W2014920226 creator A5029638028 @default.
• W2014920226 creator A5030235690 @default.
• W2014920226 creator A5060254766 @default.
• W2014920226 creator A5091832825 @default.
• W2014920226 date "1983-07-01" @default.
• W2014920226 modified "2023-09-27" @default.
• W2014920226 title "Prolonged hypoperfusion in the cerebral cortex following cardiac arrest and resuscitation in dogs" @default.
• W2014920226 cites W1986656594 @default.
• W2014920226 cites W1998458980 @default.
• W2014920226 cites W2024773521 @default.
• W2014920226 cites W2029591017 @default.
• W2014920226 cites W2073770992 @default.
• W2014920226 cites W2078829969 @default.
• W2014920226 cites W2087930938 @default.
• W2014920226 cites W2123933546 @default.
• W2014920226 cites W2166683087 @default.
• W2014920226 doi "https://doi.org/10.1016/s0196-0644(83)80334-5" @default.
• W2014920226 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6881631" @default.
• W2014920226 hasPublicationYear "1983" @default.
• W2014920226 type Work @default.
• W2014920226 sameAs 2014920226 @default.
• W2014920226 citedByCount "32" @default.
• W2014920226 countsByYear W20149202262022 @default.
• W2014920226 countsByYear W20149202262023 @default.
• W2014920226 crossrefType "journal-article" @default.
• W2014920226 hasAuthorship W2014920226A5005962993 @default.
• W2014920226 hasAuthorship W2014920226A5011056310 @default.
• W2014920226 hasAuthorship W2014920226A5016620154 @default.
• W2014920226 hasAuthorship W2014920226A5024880747 @default.
• W2014920226 hasAuthorship W2014920226A5029638028 @default.
• W2014920226 hasAuthorship W2014920226A5030235690 @default.
• W2014920226 hasAuthorship W2014920226A5060254766 @default.
• W2014920226 hasAuthorship W2014920226A5091832825 @default.
• W2014920226 hasConcept C139940330 @default.
• W2014920226 hasConcept C146957229 @default.
• W2014920226 hasConcept C154281038 @default.
• W2014920226 hasConcept C157767197 @default.
• W2014920226 hasConcept C164705383 @default.
• W2014920226 hasConcept C178853913 @default.
• W2014920226 hasConcept C2777055891 @default.
• W2014920226 hasConcept C2777795826 @default.
• W2014920226 hasConcept C2777862461 @default.
• W2014920226 hasConcept C2778165595 @default.
• W2014920226 hasConcept C2778619729 @default.
• W2014920226 hasConcept C42219234 @default.
• W2014920226 hasConcept C71924100 @default.
• W2014920226 hasConceptScore W2014920226C139940330 @default.
• W2014920226 hasConceptScore W2014920226C146957229 @default.
• W2014920226 hasConceptScore W2014920226C154281038 @default.
• W2014920226 hasConceptScore W2014920226C157767197 @default.
• W2014920226 hasConceptScore W2014920226C164705383 @default.
• W2014920226 hasConceptScore W2014920226C178853913 @default.
• W2014920226 hasConceptScore W2014920226C2777055891 @default.
• W2014920226 hasConceptScore W2014920226C2777795826 @default.
• W2014920226 hasConceptScore W2014920226C2777862461 @default.
• W2014920226 hasConceptScore W2014920226C2778165595 @default.
• W2014920226 hasConceptScore W2014920226C2778619729 @default.
• W2014920226 hasConceptScore W2014920226C42219234 @default.
• W2014920226 hasConceptScore W2014920226C71924100 @default.
• W2014920226 hasIssue "7" @default.
• W2014920226 hasLocation W20149202261 @default.
• W2014920226 hasLocation W20149202262 @default.
• W2014920226 hasOpenAccess W2014920226 @default.
• W2014920226 hasPrimaryLocation W20149202261 @default.
• W2014920226 hasRelatedWork W151298415 @default.
• W2014920226 hasRelatedWork W1990484414 @default.
• W2014920226 hasRelatedWork W2026216854 @default.
• W2014920226 hasRelatedWork W2044924835 @default.
• W2014920226 hasRelatedWork W2080889319 @default.
• W2014920226 hasRelatedWork W2098746076 @default.
• W2014920226 hasRelatedWork W2347293783 @default.
• W2014920226 hasRelatedWork W3149051618 @default.
• W2014920226 hasRelatedWork W3160603681 @default.
• W2014920226 hasRelatedWork W349559184 @default.
• W2014920226 hasVolume "12" @default.
• W2014920226 isParatext "false" @default.
• W2014920226 isRetracted "false" @default.
• W2014920226 magId "2014920226" @default.
• W2014920226 workType "article" @default.