FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014920600> ?p ?o ?g. }

• W2014920600 abstract "Abstract Background To assess the possibility of hepatocarcinoma-intestine-pancreas/pancreatitis-associated protein (HIP/PAP) as a biological marker for detecting Bladder cancer (BCa), we examined the expression of HIP/PAP in both BCa specimens and BCa cell lines and measured HIP/PAP levels in urine from patients with BCa. Methods HIP/PAP expression in BCa samples was evaluated by western blot analysis, and urinary levels of HIP/PAP in patients with BCa were measured by enzyme-linked immunosorbent assay. Urine samples were collected from 10 healthy volunteers and 109 with benign urological disorders as controls, and from 101 patients who were diagnosed with BCa. Results HIP/PAP was highly expressed in BCa samples as compared with control bladder. Urinary HIP/PAP concentrations were significantly higher in BCa patients than in controls (median value; 3.184 pg/mL vs. 55.200 pg/mL, P <0.0001, by Mann–Whitney U test). Urinary HIP/PAP levels in BCa patients correlated positively with pathological T stages and progression-risk groups among non-muscle invasive BCa (P = 0.0008, by Kruskal-Wallis test). Regarding the recurrence-risk classifications of non-muscle invasive BCa, the urinary levels of HIP/PAP were significantly higher in the intermediate than in the low risk group (P = 0.0002, by Mann–Whitney U test). Based on a cut-off of 8.5 pg/mL, the ability of urinary HIP/PAP levels to detect BCa had a sensitivity of 80.2%, specificity of 78.2%, positive predictive value (PPV) of 75.7%, and negative predictive value (NPV) of 82.3%. Conclusions HIP/PAP was abundantly expressed in BCa, and the urinary levels of HIP/PAP could be a novel and potent biomarker for detection of BCa, and also for predicting the risks of recurrence- and progression-risk of non-muscle invasive BCa. A large scale study will be needed to establish the usefulness of this biomarker." @default.
• W2014920600 created "2016-06-24" @default.
• W2014920600 creator A5000880725 @default.
• W2014920600 creator A5023252826 @default.
• W2014920600 creator A5027578308 @default.
• W2014920600 creator A5056531353 @default.
• W2014920600 creator A5066948009 @default.
• W2014920600 creator A5070072005 @default.
• W2014920600 creator A5075627852 @default.
• W2014920600 creator A5083468064 @default.
• W2014920600 date "2012-09-04" @default.
• W2014920600 modified "2023-10-16" @default.
• W2014920600 title "Urinary levels of Hepatocarcinoma-intestine-pancreas/Pancreatitis-associated protein as a diagnostic biomarker in patients with bladder cancer" @default.
• W2014920600 cites W1507637689 @default.
• W2014920600 cites W1531601693 @default.
• W2014920600 cites W1948071987 @default.
• W2014920600 cites W1977956593 @default.
• W2014920600 cites W1998275232 @default.
• W2014920600 cites W2000305974 @default.
• W2014920600 cites W2004697957 @default.
• W2014920600 cites W2014329854 @default.
• W2014920600 cites W2017265645 @default.
• W2014920600 cites W2017409567 @default.
• W2014920600 cites W2019459487 @default.
• W2014920600 cites W2040076185 @default.
• W2014920600 cites W2041095157 @default.
• W2014920600 cites W2048046930 @default.
• W2014920600 cites W2075367492 @default.
• W2014920600 cites W2091905768 @default.
• W2014920600 cites W2098124376 @default.
• W2014920600 cites W2102754351 @default.
• W2014920600 cites W2106787323 @default.
• W2014920600 cites W2113365833 @default.
• W2014920600 cites W2141237356 @default.
• W2014920600 cites W2141707461 @default.
• W2014920600 cites W2151364861 @default.
• W2014920600 cites W2157747565 @default.
• W2014920600 cites W2222191055 @default.
• W2014920600 cites W2402487223 @default.
• W2014920600 cites W4242355710 @default.
• W2014920600 cites W71249776 @default.
• W2014920600 doi "https://doi.org/10.1186/1471-2490-12-24" @default.
• W2014920600 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3487857" @default.
• W2014920600 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22943287" @default.
• W2014920600 hasPublicationYear "2012" @default.
• W2014920600 type Work @default.
• W2014920600 sameAs 2014920600 @default.
• W2014920600 citedByCount "6" @default.
• W2014920600 countsByYear W20149206002013 @default.
• W2014920600 countsByYear W20149206002015 @default.
• W2014920600 countsByYear W20149206002016 @default.
• W2014920600 countsByYear W20149206002021 @default.
• W2014920600 countsByYear W20149206002023 @default.
• W2014920600 crossrefType "journal-article" @default.
• W2014920600 hasAuthorship W2014920600A5000880725 @default.
• W2014920600 hasAuthorship W2014920600A5023252826 @default.
• W2014920600 hasAuthorship W2014920600A5027578308 @default.
• W2014920600 hasAuthorship W2014920600A5056531353 @default.
• W2014920600 hasAuthorship W2014920600A5066948009 @default.
• W2014920600 hasAuthorship W2014920600A5070072005 @default.
• W2014920600 hasAuthorship W2014920600A5075627852 @default.
• W2014920600 hasAuthorship W2014920600A5083468064 @default.
• W2014920600 hasBestOaLocation W20149206001 @default.
• W2014920600 hasConcept C121608353 @default.
• W2014920600 hasConcept C126322002 @default.
• W2014920600 hasConcept C126894567 @default.
• W2014920600 hasConcept C12868164 @default.
• W2014920600 hasConcept C207886595 @default.
• W2014920600 hasConcept C2775967933 @default.
• W2014920600 hasConcept C2778764654 @default.
• W2014920600 hasConcept C2779762690 @default.
• W2014920600 hasConcept C2780026642 @default.
• W2014920600 hasConcept C2780210213 @default.
• W2014920600 hasConcept C2780352672 @default.
• W2014920600 hasConcept C2781197716 @default.
• W2014920600 hasConcept C55493867 @default.
• W2014920600 hasConcept C71924100 @default.
• W2014920600 hasConcept C77411442 @default.
• W2014920600 hasConcept C86803240 @default.
• W2014920600 hasConcept C90924648 @default.
• W2014920600 hasConceptScore W2014920600C121608353 @default.
• W2014920600 hasConceptScore W2014920600C126322002 @default.
• W2014920600 hasConceptScore W2014920600C126894567 @default.
• W2014920600 hasConceptScore W2014920600C12868164 @default.
• W2014920600 hasConceptScore W2014920600C207886595 @default.
• W2014920600 hasConceptScore W2014920600C2775967933 @default.
• W2014920600 hasConceptScore W2014920600C2778764654 @default.
• W2014920600 hasConceptScore W2014920600C2779762690 @default.
• W2014920600 hasConceptScore W2014920600C2780026642 @default.
• W2014920600 hasConceptScore W2014920600C2780210213 @default.
• W2014920600 hasConceptScore W2014920600C2780352672 @default.
• W2014920600 hasConceptScore W2014920600C2781197716 @default.
• W2014920600 hasConceptScore W2014920600C55493867 @default.
• W2014920600 hasConceptScore W2014920600C71924100 @default.
• W2014920600 hasConceptScore W2014920600C77411442 @default.
• W2014920600 hasConceptScore W2014920600C86803240 @default.
• W2014920600 hasConceptScore W2014920600C90924648 @default.
• W2014920600 hasIssue "1" @default.
• W2014920600 hasLocation W20149206001 @default.
• W2014920600 hasLocation W20149206002 @default.

• next