FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014955209> ?p ?o ?g. }

• W2014955209 endingPage "e93297" @default.
• W2014955209 startingPage "e93297" @default.
• W2014955209 abstract "Acute kidney injury (AKI) is a syndrome characterized by the rapid loss of the kidney excretory function and is strongly associated with increased early and long-term patient morbidity and mortality. Early diagnosis of AKI is challenging; therefore we profiled plasma microRNA in an effort to identify potential diagnostic circulating markers of renal failure. The goal of the present study was to investigate the dynamic relationship of circulating and renal microRNA profiles within the first 24 hours after bilateral ischemia-reperfusion kidney injury in mice.Bilateral renal ischemia was induced in C57Bl/6 mice (n = 10 per group) by clamping the renal pedicle for 27 min. Ischemia-reperfusion caused highly reproducible, progressive, concordant elevation of miR-714, miR-1188, miR-1897-3p, miR-877*, and miR-1224 in plasma and kidneys at 3, 6 and 24 hours after acute kidney injury compared to the sham-operated mice (n = 5). These dynamics correlated with histologic findings of kidney injury and with a conventional plasma marker of renal dysfunction (creatinine). Pathway analysis revealed close association between miR-1897-3p and Nucks1 gene expression, which putative downstream targets include genes linked to renal injury, inflammation and apoptosis.Systematic profiling of renal and plasma microRNAs in the early stages of experimental AKI provides the first step in advancing circulating microRNAs to the level of promising novel biomarkers." @default.
• W2014955209 created "2016-06-24" @default.
• W2014955209 creator A5032725637 @default.
• W2014955209 creator A5043811206 @default.
• W2014955209 creator A5055223956 @default.
• W2014955209 creator A5066150506 @default.
• W2014955209 creator A5078391700 @default.
• W2014955209 creator A5081598499 @default.
• W2014955209 creator A5088109399 @default.
• W2014955209 creator A5088982303 @default.
• W2014955209 date "2014-04-02" @default.
• W2014955209 modified "2023-09-30" @default.
• W2014955209 title "Concordant Changes of Plasma and Kidney MicroRNA in the Early Stages of Acute Kidney Injury: Time Course in a Mouse Model of Bilateral Renal Ischemia-Reperfusion" @default.
• W2014955209 cites W1605178647 @default.
• W2014955209 cites W1891794422 @default.
• W2014955209 cites W1965191283 @default.
• W2014955209 cites W1969143310 @default.
• W2014955209 cites W1975862909 @default.
• W2014955209 cites W1990656514 @default.
• W2014955209 cites W1992157860 @default.
• W2014955209 cites W2008971670 @default.
• W2014955209 cites W2015918274 @default.
• W2014955209 cites W2017426710 @default.
• W2014955209 cites W2026570544 @default.
• W2014955209 cites W2036178413 @default.
• W2014955209 cites W2041509376 @default.
• W2014955209 cites W2044832480 @default.
• W2014955209 cites W2056106092 @default.
• W2014955209 cites W2059073003 @default.
• W2014955209 cites W2066342751 @default.
• W2014955209 cites W2070571588 @default.
• W2014955209 cites W2083381199 @default.
• W2014955209 cites W2105679485 @default.
• W2014955209 cites W2112192177 @default.
• W2014955209 cites W2112959832 @default.
• W2014955209 cites W2137257434 @default.
• W2014955209 cites W2146081758 @default.
• W2014955209 cites W2147575530 @default.
• W2014955209 cites W2148150383 @default.
• W2014955209 cites W2151187882 @default.
• W2014955209 cites W2155886511 @default.
• W2014955209 cites W2156791331 @default.
• W2014955209 cites W2160427593 @default.
• W2014955209 cites W2611351791 @default.
• W2014955209 cites W2093398575 @default.
• W2014955209 doi "https://doi.org/10.1371/journal.pone.0093297" @default.
• W2014955209 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3973691" @default.
• W2014955209 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24695114" @default.
• W2014955209 hasPublicationYear "2014" @default.
• W2014955209 type Work @default.
• W2014955209 sameAs 2014955209 @default.
• W2014955209 citedByCount "41" @default.
• W2014955209 countsByYear W20149552092014 @default.
• W2014955209 countsByYear W20149552092015 @default.
• W2014955209 countsByYear W20149552092016 @default.
• W2014955209 countsByYear W20149552092017 @default.
• W2014955209 countsByYear W20149552092018 @default.
• W2014955209 countsByYear W20149552092019 @default.
• W2014955209 countsByYear W20149552092020 @default.
• W2014955209 countsByYear W20149552092021 @default.
• W2014955209 countsByYear W20149552092022 @default.
• W2014955209 countsByYear W20149552092023 @default.
• W2014955209 crossrefType "journal-article" @default.
• W2014955209 hasAuthorship W2014955209A5032725637 @default.
• W2014955209 hasAuthorship W2014955209A5043811206 @default.
• W2014955209 hasAuthorship W2014955209A5055223956 @default.
• W2014955209 hasAuthorship W2014955209A5066150506 @default.
• W2014955209 hasAuthorship W2014955209A5078391700 @default.
• W2014955209 hasAuthorship W2014955209A5081598499 @default.
• W2014955209 hasAuthorship W2014955209A5088109399 @default.
• W2014955209 hasAuthorship W2014955209A5088982303 @default.
• W2014955209 hasBestOaLocation W20149552091 @default.
• W2014955209 hasConcept C126322002 @default.
• W2014955209 hasConcept C126894567 @default.
• W2014955209 hasConcept C142724271 @default.
• W2014955209 hasConcept C159641895 @default.
• W2014955209 hasConcept C2780091579 @default.
• W2014955209 hasConcept C2780114680 @default.
• W2014955209 hasConcept C2780306776 @default.
• W2014955209 hasConcept C2780472472 @default.
• W2014955209 hasConcept C2780721119 @default.
• W2014955209 hasConcept C541997718 @default.
• W2014955209 hasConcept C54847362 @default.
• W2014955209 hasConcept C71924100 @default.
• W2014955209 hasConceptScore W2014955209C126322002 @default.
• W2014955209 hasConceptScore W2014955209C126894567 @default.
• W2014955209 hasConceptScore W2014955209C142724271 @default.
• W2014955209 hasConceptScore W2014955209C159641895 @default.
• W2014955209 hasConceptScore W2014955209C2780091579 @default.
• W2014955209 hasConceptScore W2014955209C2780114680 @default.
• W2014955209 hasConceptScore W2014955209C2780306776 @default.
• W2014955209 hasConceptScore W2014955209C2780472472 @default.
• W2014955209 hasConceptScore W2014955209C2780721119 @default.
• W2014955209 hasConceptScore W2014955209C541997718 @default.
• W2014955209 hasConceptScore W2014955209C54847362 @default.
• W2014955209 hasConceptScore W2014955209C71924100 @default.
• W2014955209 hasIssue "4" @default.
• W2014955209 hasLocation W20149552091 @default.

• next