FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014990551> ?p ?o ?g. }

• W2014990551 endingPage "953" @default.
• W2014990551 startingPage "943" @default.
• W2014990551 abstract "Previous data have suggested that rofecoxib, a cyclooxygenase (COX)-2-specific inhibitor, had analgesic effects similar to those of the nonsteroidal anti-inflammatory drugs when tested in the post-dental surgery pain model. The objective of this parallel-group, double-masked, randomized, placebo- and active comparator-controlled clinical trial was to assess more fully the analgesic efficacy of rofecoxib in the treatment of postoperative dental pain. After dental surgery, 151 patients (50.3% women; mean age, 18.3 years; 93.4% white) experiencing moderate-to-severe pain were to receive a single dose of placebo, rofecoxib 50 mg, or ibuprofen 400 mg. Analgesic efficacy was assessed for up to 24 hours postdose using self-administered questionnaires. Tolerability was assessed using spontaneous reports of adverse experiences, physical findings, and laboratory measurements. The results of this study demonstrated that rofecoxib 50 mg was more effective than placebo on all measures of analgesic efficacy. Rofecoxib 50 mg exhibited overall analgesic effects, onset of analgesia, and peak analgesic effects that were not significantly different from those of ibuprofen 400 mg, with a significantly longer duration of action (P < 0.05). We concluded that rofecoxib was efficacious in the treatment of postoperative dental pain and that COX-2-derived prostanoids play a role in treatment of the pain associated with dental surgery." @default.
• W2014990551 created "2016-06-24" @default.
• W2014990551 creator A5005007652 @default.
• W2014990551 creator A5023569072 @default.
• W2014990551 creator A5024204347 @default.
• W2014990551 creator A5038091130 @default.
• W2014990551 creator A5070310902 @default.
• W2014990551 creator A5077849086 @default.
• W2014990551 date "1999-06-01" @default.
• W2014990551 modified "2023-10-10" @default.
• W2014990551 title "Analgesic efficacy of the cyclooxygenase-2-specific inhibitor rofecoxib in post-dental surgery pain: A randomized, controlled trial" @default.
• W2014990551 cites W1536681507 @default.
• W2014990551 cites W1580788756 @default.
• W2014990551 cites W1828786787 @default.
• W2014990551 cites W1921815852 @default.
• W2014990551 cites W1961470626 @default.
• W2014990551 cites W1971917612 @default.
• W2014990551 cites W1973948212 @default.
• W2014990551 cites W1979605401 @default.
• W2014990551 cites W1981145090 @default.
• W2014990551 cites W1981662925 @default.
• W2014990551 cites W2008424322 @default.
• W2014990551 cites W2026230912 @default.
• W2014990551 cites W2041777500 @default.
• W2014990551 cites W2052355330 @default.
• W2014990551 cites W2070386995 @default.
• W2014990551 cites W2077536050 @default.
• W2014990551 cites W2080197694 @default.
• W2014990551 cites W2103766497 @default.
• W2014990551 cites W2110139999 @default.
• W2014990551 cites W2293977658 @default.
• W2014990551 doi "https://doi.org/10.1016/s0149-2918(99)80016-2" @default.
• W2014990551 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10440619" @default.
• W2014990551 hasPublicationYear "1999" @default.
• W2014990551 type Work @default.
• W2014990551 sameAs 2014990551 @default.
• W2014990551 citedByCount "211" @default.
• W2014990551 countsByYear W20149905512012 @default.
• W2014990551 countsByYear W20149905512013 @default.
• W2014990551 countsByYear W20149905512014 @default.
• W2014990551 countsByYear W20149905512015 @default.
• W2014990551 countsByYear W20149905512016 @default.
• W2014990551 countsByYear W20149905512018 @default.
• W2014990551 countsByYear W20149905512019 @default.
• W2014990551 countsByYear W20149905512020 @default.
• W2014990551 countsByYear W20149905512023 @default.
• W2014990551 crossrefType "journal-article" @default.
• W2014990551 hasAuthorship W2014990551A5005007652 @default.
• W2014990551 hasAuthorship W2014990551A5023569072 @default.
• W2014990551 hasAuthorship W2014990551A5024204347 @default.
• W2014990551 hasAuthorship W2014990551A5038091130 @default.
• W2014990551 hasAuthorship W2014990551A5070310902 @default.
• W2014990551 hasAuthorship W2014990551A5077849086 @default.
• W2014990551 hasConcept C126322002 @default.
• W2014990551 hasConcept C141071460 @default.
• W2014990551 hasConcept C142724271 @default.
• W2014990551 hasConcept C16328479 @default.
• W2014990551 hasConcept C168563851 @default.
• W2014990551 hasConcept C181199279 @default.
• W2014990551 hasConcept C185592680 @default.
• W2014990551 hasConcept C197934379 @default.
• W2014990551 hasConcept C199343813 @default.
• W2014990551 hasConcept C204787440 @default.
• W2014990551 hasConcept C27081682 @default.
• W2014990551 hasConcept C2778375690 @default.
• W2014990551 hasConcept C2778582115 @default.
• W2014990551 hasConcept C2779689624 @default.
• W2014990551 hasConcept C2779826273 @default.
• W2014990551 hasConcept C2779944601 @default.
• W2014990551 hasConcept C2780820201 @default.
• W2014990551 hasConcept C42219234 @default.
• W2014990551 hasConcept C55493867 @default.
• W2014990551 hasConcept C71924100 @default.
• W2014990551 hasConcept C98274493 @default.
• W2014990551 hasConceptScore W2014990551C126322002 @default.
• W2014990551 hasConceptScore W2014990551C141071460 @default.
• W2014990551 hasConceptScore W2014990551C142724271 @default.
• W2014990551 hasConceptScore W2014990551C16328479 @default.
• W2014990551 hasConceptScore W2014990551C168563851 @default.
• W2014990551 hasConceptScore W2014990551C181199279 @default.
• W2014990551 hasConceptScore W2014990551C185592680 @default.
• W2014990551 hasConceptScore W2014990551C197934379 @default.
• W2014990551 hasConceptScore W2014990551C199343813 @default.
• W2014990551 hasConceptScore W2014990551C204787440 @default.
• W2014990551 hasConceptScore W2014990551C27081682 @default.
• W2014990551 hasConceptScore W2014990551C2778375690 @default.
• W2014990551 hasConceptScore W2014990551C2778582115 @default.
• W2014990551 hasConceptScore W2014990551C2779689624 @default.
• W2014990551 hasConceptScore W2014990551C2779826273 @default.
• W2014990551 hasConceptScore W2014990551C2779944601 @default.
• W2014990551 hasConceptScore W2014990551C2780820201 @default.
• W2014990551 hasConceptScore W2014990551C42219234 @default.
• W2014990551 hasConceptScore W2014990551C55493867 @default.
• W2014990551 hasConceptScore W2014990551C71924100 @default.
• W2014990551 hasConceptScore W2014990551C98274493 @default.
• W2014990551 hasIssue "6" @default.
• W2014990551 hasLocation W20149905511 @default.
• W2014990551 hasLocation W20149905512 @default.

• next