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- W2014991049 abstract "AbstractLayer by layer (LbL) self-assemble technique attracts much attention in the field of drug delivery because of its simplicity in procedure and fine tuning of the microstructure. Considering the acting force between the assemble material and the drug molecule, the authors chose a β-cyclodextrin derivative as assemble material. Therefore, a polycarboxymethyl-β-cyclodextrin (polyCM-β-CD)/polyetherimide (PEI) multilayer for drug delivery was designed and constructed in this work. Orfloxacin was loaded into the multilayer during the self-assemble procedure by incorporating drugs in the PEI assemble solution as well as in polyCM-β-CD assemble solution, which was confirmed by the largest drug absorbance of UV spectrum. Twenty assembled layers were chosen in view of the relative stable properties of the hydrogel surface. Since the pH value was an important factor to the properties of the polyelectrolyte multilayer, the effects of pH value on the drug release behaviour were further investigated in this work..." @default.
- W2014991049 created "2016-06-24" @default.
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- W2014991049 date "2014-11-13" @default.
- W2014991049 modified "2023-09-25" @default.
- W2014991049 title "Drug release behaviour from drug loaded LBL multilayer on hydrogel" @default.
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- W2014991049 doi "https://doi.org/10.1179/1753555714y.0000000233" @default.
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