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- W2014998020 abstract "British Journal of Clinical PharmacologyVolume 13, Issue 5 p. 737-740 Free Access 6 beta-hydroxycortisol excretion in relation to polymorphic N-oxidation of sparteine [letter] BK Park, BK ParkSearch for more papers by this authorM Eichelbaum, M EichelbaumSearch for more papers by this authorEE Ohnhaus, EE OhnhausSearch for more papers by this author BK Park, BK ParkSearch for more papers by this authorM Eichelbaum, M EichelbaumSearch for more papers by this authorEE Ohnhaus, EE OhnhausSearch for more papers by this author First published: May 1982 https://doi.org/10.1111/j.1365-2125.1982.tb01448.xCitations: 8AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL References BERTILSSON, L., DENGLER, H.J., EICHELBAUM, M. & SCHULZ, H.U. (1980a). Pharmacogenetic covariation of defective N-oxidation of sparteine and 4-hydroxylation of debrisoquine. Eur. J. Clin. Pharmac., 17, 153– 155. BERTILSSON, L., EICHELBAUM, M., MELSTROM, B., SAWE, J., SCHULZ, H.U. & SJOQVIST, F. (1980b). Nortriptyline and antipyrine clearance in relation to debrisoquine hydroxylation in man. Life Sci., 27, 1673– 1677. BOOBIS, A.R., KAHN, G.C., WHYTE, C., BRODIE, M.J. & DAVIES, D.S. (1981). Biphasic O-deethylation of phenacetin and 7-ethoxycoumarin by human and rat liver microsomal fractions. Biochem. Pharmac., 30, 2451– 2456. CHALLINER, M.R., PARK, B.K., ODUM, J., ORTON, T.C. & PARKER, G.L. (1980). The effect of phenobarbitone on urinary 6/3-hydroxycortisol excretion and hepatic enzyme activity in the marmoset monkey (Callithrix jacchus). Biochem. Pharmac., 29, 3319– 3324. CHALLINER, M.R., PARK, B.K., ODUM, J. & ORTON, T.C. (1981). The effect of 3-methylcholanthrene on urinary 6/3-hydroxycortisol excretion and hepatic enzyme activity in marmoset monkey (Callithrix jacchus). Biochem. Pharmac., 30, 2131– 2134. DANHOF, M., IDLE, J.R., TENNISSEN, M.W.E., SLOANE, T.P., BREIMER, D.D. & SMITH, R.L. (1981). Influence of the genetically controlled deficiency in debrisoquine hydroxylation on antipyrine metabolite formation. Pharmacology., 22, 349– 358. DENGLER, H.J. & EICHELBAUM, M. (1977). Polymorphismen und Defekte des Arzneimittelstoff-wechsels als Ursache toxischer Reaktionen. Arzneim. Forsch. (Drug Res.), 27, 1836– 1844. EICHELBAUM, M., SPANNBRUCKER, N., STEINCKE, B. & DENGLER H.J (1979). Defective N-oxidation of sparteine in man: A new pharmacogenetic defect. Eur. J. clin. Pharmac., 16, 183– 187. EICHELBAUM, M., BERTILSSON, L., SAWE, J. & ZEKORN, C. (1982). Polymorphic oxidation of sparteine and debrisoquine: Related pharmacogenetic entities. Clin. Pharmac. Ther. (in press). FRANTZ, A.G., KATZ, F.H. & JAILER, R.W.J. (1961). 6/3-hydroxycortisol and other polar corticosteroids: Measurements and significance in human urine. J. clin. Endrocrin., 21, 129O– 1303. INABA, T., OTTON, S.V. & KALOW, W. (1980). Deficient metabolism of debrisoquine and sparteine. Clin. Pharmac. Ther., 27, 547– 549. MAHGOUB, A., IDLE, J.R., DRING, L.G., LANCASTER, R. & SMITH, R.L. (1977). Polymorphic hydroxylation of debrisoquine in man. Lancet, ii, 584– 586. OHNHAUS, E.E. & PARK, B.K. (1979). Measurement of urinary 6/3-hydroxycortisol excretion as an in vivo parameter in the clinical assessment of the microsomal enzyme inducing capacity of antipyrine, phenobarbitone and rifampicin. Eur. J. clin. Pharmac., 13, 139– 145. PARK, B.K. (1978). A direct radioimmunoassay for 6β-hydroxycortisol in human urine. J. steroid Biochem., 9, 963– 966. PARK, B.K. (1981). Assessment of urinary 6β-hydroxycortisol as an in vivo index of mixed function oxygenase activity. Br. J. clin. Pharmac., 12, 97– 102. SANGHVI, A., WRIGHT, C., PARIKH, B. & DESAI, H. (1973). Urinary 17-hydroxycorticosteroid determination with p-hydrazinobenezene-sulfonic acid-phosphoric acid. Am. J. clin. Path., 60, 684– 690. SPITELLER, M. & SPITELER, G. (1978). Structural elucidation of sparteine metabolites. In Biological oxidation of nitrogen, ed. J. Gorrod pp. 109– 112. Amsterdam: Elsevier. Citing Literature Volume13, Issue5May 1982Pages 737-740 ReferencesRelatedInformation" @default.
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