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- W2015011552 abstract "Background. We tested the hypothesis that warm-humidified carbon dioxide (CO 2 ) insufflation would reduce postoperative pain and morphine requirement compared to cold-dry CO 2 insufflation. Methods. A double-blinded, randomized, controlled trial was conducted to compare warm, humidified CO 2 and cold-dry CO 2 . Patients with benign uterine diseases were randomized to either treatment (<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M1><mml:mi>n</mml:mi><mml:mo>=</mml:mo><mml:mn>48</mml:mn></mml:math>) or control (<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M2><mml:mi>n</mml:mi><mml:mo>=</mml:mo><mml:mn>49</mml:mn></mml:math>) group during laparoscopically assisted vaginal hysterectomy. Primary endpoints of the study were rest pain, movement pain, shoulder-tip pain, and cough pain at 2, 4, 6, 24, and 48 hours postoperatively, measured by visual analogue scale. Secondary outcomes were morphine consumption, rejected boli, temperature change, recovery room stay, and length of hospital stay. Results. There were no significant differences in all baseline characteristics. Shoulder-tip pain at 6 h postoperatively was significantly reduced in the intervention group. Pain at rest, movement pain, and cough pain did not differ. Total morphine consumption and rejected boli at 24 h postoperatively were significantly higher in the control group. Temperature change, recovery room stay, and length of hospital were similar. Conclusions. Warm, humidified insufflation gas significantly reduces postoperative shoulder-tip pain as well as morphine demand. This trial is registered with Clinical Trial Registration Number DRKS00003853 (German Clinical Trials Register (DRKS))." @default.
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- W2015011552 date "2015-01-01" @default.
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- W2015011552 title "Insufflation with Humidified and Heated Carbon Dioxide in Short-Term Laparoscopy: A Double-Blinded Randomized Controlled Trial" @default.
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- W2015011552 doi "https://doi.org/10.1155/2015/412618" @default.
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