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• W2015016878 abstract "The mechanisms underlying spike time coding in auditory system are not well understood. Despite of several models proposed to describe the first spike latency (FSL), there is no comparison of their respective performance. Here, based on FSL data from the central nucleus of inferior colliculus (CIC) in mouse to tone stimuli with varying rise function, rise time, and amplitude, we examined the previous models by comparing the recorded FSL with derived the FSL, respectively. We found that the LIEFTS (leaky integration, event formation, temporal summation) threshold model produced better match with the recorded data than other models. In addition, the model suggested that the short time constants derived from the FSL data (<2 ms) cannot be attributed to IC neurons themselves (normally longer than 10 ms), but are similar to those for the inner hair cells (around 1.4 ms). Our results suggested that LIEFTS threshold model is a better fit for FSL, and FSL properties in central neurons can be inherited along the central auditory pathway, likely through faithful relays from the peripheral origins." @default.
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• W2015016878 date "2011-01-01" @default.
• W2015016878 modified "2023-10-15" @default.
• W2015016878 title "Response property of inferior collicular neurons inherited from peripheral origin in mouse" @default.
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• W2015016878 doi "https://doi.org/10.1016/j.brainres.2010.11.011" @default.
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