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• W2015018426 abstract "Temporal relationships among circulating concentrations of nitric oxide metabolites (NOM), progesterone (P4), and luteinizing hormone (LH) within the hours of a PGFM pulse were studied during luteolysis in heifers. The peak of a PGFM pulse was designated Hour 0. All of the following increases and decreases were significant. Within a spontaneous PGFM pulse (experiment 1; n = 7), concentrations of P4 and LH decreased between Hours -1 and 0 and increased between Hours 0 and 1; NOM increased between Hours -1 and 2. In experiment 2, PGFM pulses were simulated by intrauterine infusion of PGF2α (PGF group, n = 6), and another group was also treated with acyline to inhibit LH secretion (acyline-PGF group, n = 6). Averaged over the two groups, concentration of P4 decreased between Hours -2 and 0, increased (rebounded) between Hours 0 and 1, and decreased after Hour 2. In the PGF group, concentration of LH decreased between Hours -2 and -0.5 and increased between Hour 0 and Hour 1.5 to a maximum at Hour 1.5; NOM decreased between Hours -2 and -1.5 and increased between Hours 0 and 1.5. In the acyline-PGF group, the effect of hour was not significant for concentrations of LH and NOM. The absence of an increase in NOM concentration when LH was inhibited is a novel finding. The hypotheses were supported that concentrations of LH and NOM are temporally related, and LH has a role in the increase in NOM within the hours of a PGFM pulse." @default.
• W2015018426 created "2016-06-24" @default.
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• W2015018426 date "2015-01-01" @default.
• W2015018426 modified "2023-09-27" @default.
• W2015018426 title "Circulating nitric oxide metabolites during luteolysis and the effect of luteinizing hormone on circulating nitric oxide metabolites in heifers" @default.
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• W2015018426 doi "https://doi.org/10.1016/j.theriogenology.2014.09.010" @default.
• W2015018426 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25442387" @default.
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