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- W2015054684 abstract "Purpose: Diffusion tensor imaging (DTI) is an inherently quantitative imaging technique that measures thediffusivities of water molecules in tissue. However, the accuracy of DTI measurements depends on manyfactors such S/N ratio and magnet field strength. Therefore, before quantitative assessment of tumorprogression based on DTI metric changes can be made with confidence, one have to assess the accuracy orvariance in the DTI metrics. This is especially important for multi-institutional clinical trials or for largeinstitutions where patients may be imaged on multiple MR scanners at multiple times in follow up studies.In this presentation, we studied the feasibility of using CSF as an internal QC marker for data acquisitionand processing qualities. Method: ADC and FA of CSF for brain tumor patients' DTI studies (total of 85scans over three years) were analyzed. In addition, a phantom was used to check the inherent variations ofthe MR systems. Results: The results show that the coefficient of variations for ADC and FA are 8.4% and13.2% in CSF among all patients. For all DTI scans done on 1.5 T scanners, they are 7.4% and 9.1%, whilefor 3T they are 9.8% and 18% respectively. Conclusion: CSF can be used as an internal QC measure of theDTI acquisition accuracy and consistency among longitude studies on patients, making it a potentiallyuseful in multi-institutional trials." @default.
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- W2015054684 date "2009-02-26" @default.
- W2015054684 modified "2023-09-23" @default.
- W2015054684 title "Using CSF as an internal quality assurance tool in diffusion tensor imaging studies of brain tumor" @default.
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- W2015054684 doi "https://doi.org/10.1117/12.812128" @default.
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