Matches in SemOpenAlex for { <https://semopenalex.org/work/W2015065245> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W2015065245 endingPage "306" @default.
- W2015065245 startingPage "302" @default.
- W2015065245 abstract "Given the variable natural history of prostate cancer, prognostic parameters are needed to help guide treatment decisions in individual patients. In some series, analysis of DNA ploidy has correlated well with prognosis. This review was performed to determine whether flow cytometry could be used to help guide treatment decisions in patients with localized carcinoma of the prostate.Two hundred consecutive patients were observed for a minimum of 10 years after radical prostatectomy. Follow-up information was incomplete in 14 patients, leaving 186 for analysis. Clinically, there were 72% Stage B tumors and 28% Stage A.Sixty percent of patients were alive with a minimum of 10 years of follow-up, and 47% apparently were tumor free. Twenty-two percent died of carcinoma of the prostate and 18% of other causes. The median time until death from prostate cancer was 6.5 years. Seventy-four percent of tumors were diploid on flow cytometry. Fifty-three percent of patients with diploid tumors survived 10 years without recurrence, whereas 20% died of carcinoma of the prostate. Aneuploid tumors were identified in 16% of the total group; 47% of these patients were alive at 10 years, whereas 24% had died of prostate cancer.Aneuploid tumors have a worse overall prognosis than diploid lesions. However, the correlation is not strong enough to allow treatment decisions on an individual patient basis. Analysis of DNA ploidy was no more accurate than Gleason histologic grading." @default.
- W2015065245 created "2016-06-24" @default.
- W2015065245 creator A5073175568 @default.
- W2015065245 date "1992-07-01" @default.
- W2015065245 modified "2023-09-25" @default.
- W2015065245 title "Management of localized prostate cancer" @default.
- W2015065245 cites W166829100 @default.
- W2015065245 cites W167081892 @default.
- W2015065245 cites W176184199 @default.
- W2015065245 cites W194609839 @default.
- W2015065245 cites W2058525489 @default.
- W2015065245 cites W2059705382 @default.
- W2015065245 cites W2134446930 @default.
- W2015065245 cites W2267688072 @default.
- W2015065245 cites W2396128216 @default.
- W2015065245 cites W2400981133 @default.
- W2015065245 cites W2408838189 @default.
- W2015065245 cites W2411693497 @default.
- W2015065245 cites W2415217636 @default.
- W2015065245 cites W2416032311 @default.
- W2015065245 cites W2419345102 @default.
- W2015065245 cites W2469820878 @default.
- W2015065245 cites W4300976303 @default.
- W2015065245 cites W44088029 @default.
- W2015065245 doi "https://doi.org/10.1002/1097-0142(19920701)70:1+<302::aid-cncr2820701318>3.0.co;2-4" @default.
- W2015065245 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1600491" @default.
- W2015065245 hasPublicationYear "1992" @default.
- W2015065245 type Work @default.
- W2015065245 sameAs 2015065245 @default.
- W2015065245 citedByCount "6" @default.
- W2015065245 countsByYear W20150652452021 @default.
- W2015065245 crossrefType "journal-article" @default.
- W2015065245 hasAuthorship W2015065245A5073175568 @default.
- W2015065245 hasBestOaLocation W20150652451 @default.
- W2015065245 hasConcept C121608353 @default.
- W2015065245 hasConcept C126322002 @default.
- W2015065245 hasConcept C126894567 @default.
- W2015065245 hasConcept C142724271 @default.
- W2015065245 hasConcept C143998085 @default.
- W2015065245 hasConcept C146357865 @default.
- W2015065245 hasConcept C151730666 @default.
- W2015065245 hasConcept C18903297 @default.
- W2015065245 hasConcept C2776235491 @default.
- W2015065245 hasConcept C2777286243 @default.
- W2015065245 hasConcept C2777546739 @default.
- W2015065245 hasConcept C2779466945 @default.
- W2015065245 hasConcept C2780192828 @default.
- W2015065245 hasConcept C71924100 @default.
- W2015065245 hasConcept C86803240 @default.
- W2015065245 hasConceptScore W2015065245C121608353 @default.
- W2015065245 hasConceptScore W2015065245C126322002 @default.
- W2015065245 hasConceptScore W2015065245C126894567 @default.
- W2015065245 hasConceptScore W2015065245C142724271 @default.
- W2015065245 hasConceptScore W2015065245C143998085 @default.
- W2015065245 hasConceptScore W2015065245C146357865 @default.
- W2015065245 hasConceptScore W2015065245C151730666 @default.
- W2015065245 hasConceptScore W2015065245C18903297 @default.
- W2015065245 hasConceptScore W2015065245C2776235491 @default.
- W2015065245 hasConceptScore W2015065245C2777286243 @default.
- W2015065245 hasConceptScore W2015065245C2777546739 @default.
- W2015065245 hasConceptScore W2015065245C2779466945 @default.
- W2015065245 hasConceptScore W2015065245C2780192828 @default.
- W2015065245 hasConceptScore W2015065245C71924100 @default.
- W2015065245 hasConceptScore W2015065245C86803240 @default.
- W2015065245 hasIssue "S1" @default.
- W2015065245 hasLocation W20150652451 @default.
- W2015065245 hasLocation W20150652452 @default.
- W2015065245 hasOpenAccess W2015065245 @default.
- W2015065245 hasPrimaryLocation W20150652451 @default.
- W2015065245 hasRelatedWork W108895284 @default.
- W2015065245 hasRelatedWork W1967410728 @default.
- W2015065245 hasRelatedWork W1982503259 @default.
- W2015065245 hasRelatedWork W1995349396 @default.
- W2015065245 hasRelatedWork W2037411085 @default.
- W2015065245 hasRelatedWork W2094977608 @default.
- W2015065245 hasRelatedWork W2118670275 @default.
- W2015065245 hasRelatedWork W2402249956 @default.
- W2015065245 hasRelatedWork W2909802736 @default.
- W2015065245 hasRelatedWork W3150909901 @default.
- W2015065245 hasVolume "70" @default.
- W2015065245 isParatext "false" @default.
- W2015065245 isRetracted "false" @default.
- W2015065245 magId "2015065245" @default.
- W2015065245 workType "article" @default.