FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2015094476> ?p ?o ?g. }

• W2015094476 endingPage "2088" @default.
• W2015094476 startingPage "2084" @default.
• W2015094476 abstract "Female transgenic mice that ectopically express high levels of human Müllerian-inhibiting substance (hMIS) under the control of the mouse metallothionein (MT) promoter lack a uterus, oviducts, and ovaries. The loss of the uterus and oviducts is consistent with the known activities for MIS. However, it is not clear if the loss of the ovaries in these transgenic females is caused by interactions of MIS with its normal receptor signaling pathway or by abnormal interactions with other transforming growth factor-beta (TGF-beta) super family receptor signaling pathways. To address this question, female mice carrying the MT-hMIS transgene that were also homozygous for a targeted deletion of the MIS type II receptor gene were generated. Although these females had high levels of circulating hMIS, they had normal reproductive tracts and ovaries with germ cells. In addition, these females were able to become pregnant and gave birth to pups. These findings demonstrate that all of the abnormalities of the reproductive system that are found in female transgenic mice that ectopically express high levels of hMIS are caused by signaling through the MIS type II receptor. These in vivo data demonstrate a high specificity for MIS and its receptor." @default.
• W2015094476 created "2016-06-24" @default.
• W2015094476 creator A5013530671 @default.
• W2015094476 creator A5059882947 @default.
• W2015094476 creator A5068328322 @default.
• W2015094476 creator A5080788580 @default.
• W2015094476 date "1999-05-01" @default.
• W2015094476 modified "2023-10-13" @default.
• W2015094476 title "High Specificity of Müllerian-Inhibiting Substance Signaling in Vivo*" @default.
• W2015094476 cites W1936821077 @default.
• W2015094476 cites W1967519389 @default.
• W2015094476 cites W1990438615 @default.
• W2015094476 cites W1991835307 @default.
• W2015094476 cites W1993692364 @default.
• W2015094476 cites W1995958544 @default.
• W2015094476 cites W2000270540 @default.
• W2015094476 cites W2019000990 @default.
• W2015094476 cites W2026489579 @default.
• W2015094476 cites W2032212583 @default.
• W2015094476 cites W2034199666 @default.
• W2015094476 cites W2062221351 @default.
• W2015094476 cites W2067336113 @default.
• W2015094476 cites W2078183232 @default.
• W2015094476 cites W2080786870 @default.
• W2015094476 cites W2080881225 @default.
• W2015094476 cites W2085971961 @default.
• W2015094476 cites W2089373281 @default.
• W2015094476 cites W2089928608 @default.
• W2015094476 cites W2099429349 @default.
• W2015094476 cites W2113652074 @default.
• W2015094476 cites W2116112998 @default.
• W2015094476 cites W2122355227 @default.
• W2015094476 cites W2131204570 @default.
• W2015094476 cites W2137320238 @default.
• W2015094476 cites W2144005229 @default.
• W2015094476 cites W2163514784 @default.
• W2015094476 cites W2166820565 @default.
• W2015094476 cites W2474895326 @default.
• W2015094476 doi "https://doi.org/10.1210/endo.140.5.6705" @default.
• W2015094476 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10218958" @default.
• W2015094476 hasPublicationYear "1999" @default.
• W2015094476 type Work @default.
• W2015094476 sameAs 2015094476 @default.
• W2015094476 citedByCount "46" @default.
• W2015094476 countsByYear W20150944762012 @default.
• W2015094476 countsByYear W20150944762013 @default.
• W2015094476 countsByYear W20150944762014 @default.
• W2015094476 countsByYear W20150944762017 @default.
• W2015094476 countsByYear W20150944762018 @default.
• W2015094476 countsByYear W20150944762019 @default.
• W2015094476 countsByYear W20150944762021 @default.
• W2015094476 countsByYear W20150944762022 @default.
• W2015094476 countsByYear W20150944762023 @default.
• W2015094476 crossrefType "journal-article" @default.
• W2015094476 hasAuthorship W2015094476A5013530671 @default.
• W2015094476 hasAuthorship W2015094476A5059882947 @default.
• W2015094476 hasAuthorship W2015094476A5068328322 @default.
• W2015094476 hasAuthorship W2015094476A5080788580 @default.
• W2015094476 hasBestOaLocation W20150944761 @default.
• W2015094476 hasConcept C102230213 @default.
• W2015094476 hasConcept C104317684 @default.
• W2015094476 hasConcept C126322002 @default.
• W2015094476 hasConcept C134018914 @default.
• W2015094476 hasConcept C141035611 @default.
• W2015094476 hasConcept C170493617 @default.
• W2015094476 hasConcept C207001950 @default.
• W2015094476 hasConcept C2778324911 @default.
• W2015094476 hasConcept C2779066055 @default.
• W2015094476 hasConcept C54355233 @default.
• W2015094476 hasConcept C62478195 @default.
• W2015094476 hasConcept C71924100 @default.
• W2015094476 hasConcept C86803240 @default.
• W2015094476 hasConcept C95444343 @default.
• W2015094476 hasConceptScore W2015094476C102230213 @default.
• W2015094476 hasConceptScore W2015094476C104317684 @default.
• W2015094476 hasConceptScore W2015094476C126322002 @default.
• W2015094476 hasConceptScore W2015094476C134018914 @default.
• W2015094476 hasConceptScore W2015094476C141035611 @default.
• W2015094476 hasConceptScore W2015094476C170493617 @default.
• W2015094476 hasConceptScore W2015094476C207001950 @default.
• W2015094476 hasConceptScore W2015094476C2778324911 @default.
• W2015094476 hasConceptScore W2015094476C2779066055 @default.
• W2015094476 hasConceptScore W2015094476C54355233 @default.
• W2015094476 hasConceptScore W2015094476C62478195 @default.
• W2015094476 hasConceptScore W2015094476C71924100 @default.
• W2015094476 hasConceptScore W2015094476C86803240 @default.
• W2015094476 hasConceptScore W2015094476C95444343 @default.
• W2015094476 hasIssue "5" @default.
• W2015094476 hasLocation W20150944761 @default.
• W2015094476 hasLocation W20150944762 @default.
• W2015094476 hasOpenAccess W2015094476 @default.
• W2015094476 hasPrimaryLocation W20150944761 @default.
• W2015094476 hasRelatedWork W1973459962 @default.
• W2015094476 hasRelatedWork W2011045295 @default.
• W2015094476 hasRelatedWork W2064668712 @default.
• W2015094476 hasRelatedWork W2070974215 @default.
• W2015094476 hasRelatedWork W2158124286 @default.
• W2015094476 hasRelatedWork W2351205382 @default.

• next